Control of gene expression is a very big topic and so I'm going to show you one cartoon to sort of tell you that it is a big topic that's really important.

基因表达的调控是个大课题,我给你们放一些动画,好让你们理解,其涉及范围之广,意义之重

耶鲁公开课 - 生物医学工程探索课程节选

I would love to be in a big, big network and have my own show with a big network.

我很想进入一个很大很大的领域，在圈内有自己的演出。

阳光总在风雨后 - SpeakingMax英语口语达人

So just to show you how big a difference it makes, let's run a couple of numbers.

让我们试试一组数字吧,如果n是1000的话。

麻省理工公开课 - 计算机科学及编程导论课程节选

before he became really big when he was here in town doing his TV show,

在他大红大紫之前，他来这里拍电视剧，

记忆犹新的乘客 - SpeakingMax英语口语达人

And yeah, it's just basically a big talent show,

同时基本上，它也仅是一个大型的达人秀，

英国的真人秀 - SpeakingMax英语口语达人