So, there's no absolutes about this, this is a general response where all the features can be different with different pathogens.
这其中并没有明确的规律,免疫应答是普遍存在的,但针对不同的病原体的应答规律各不相同
When they do that they can actually engulf the bacteria in a process called phagocytosis and break them down into antigens.
免疫细胞确实是将细菌整个吞进了肚内,这一过程称为吞噬作用,并将细菌分解成小抗原
It's how quickly, how promptly we can recover from these painful emotions-- in other words, how strong our psychological immune system is.
区别在于他们能够多么迅速,多么快速地从痛苦情绪中恢复过来-,换言之,我们的心理免疫系统有多强。
Suppose that most times and most activities were death free, but certain activities introduce the possibility of dying.
假设大部分时间和大部分活动都是死亡免疫的,但某些活动,会引起死亡的可能性。
Humoral refers to immunity in the blood and it's immunity that's in the blood in the form of antibodies.
体液免疫代表着血液中的免疫机制,血液中的免疫机制是以抗体的形式存在的
So, just an introduction to the classes of potential foreign invaders that our immune system tries to defend us against.
所以 我只是简单介绍几类,免疫系统试图抵御的潜在外来侵略者
You don't have it, you don't have any immunity to smallpox, you don't have any reason to immunity to smallpox.
你们对天花没有任何免疫力,你没有任何理由能对天花免疫
We're going to talk about how they're prepared, but it's a preparation that is intended to stimulate your immune system.
我们会讲它们是如何做准备的,它通过刺激你的免疫系统来进行准备
This is a way for the immune system to recognize things that are going wrong inside the cell protected from antibodies.
这是免疫系统识别,抗体不能识别的细胞内病变的方法
In the immune system you could think of it as an even more complex set of outcomes that occur.
免疫系统是一个,有更多复杂结果的大集合
You've all been immunized for Hepatitis B, would you be happy to hear that that's where your Hepatitis B vaccine came from?
你们都对乙型肝炎具有免疫力了,如果你知道你的乙型肝炎疫苗,是从何而来的话,你还会高兴的起来吗
In fact, the people who have been most important in understanding how the innate immune system works are people here at Yale.
事实上 在研究先天免疫系统,反应机理中,最重要的科学家就在耶鲁
Usually it's done by taking all or part of the infectious agent, and showing them to your immune system in some way.
通常它会带着全部或部分抗原介质,并以某种方式呈递给你的免疫系统
Memory cells are long lasting cells that remember this exposure and can respond very quickly on second exposure.
记忆细胞可以长时间记忆与抗原的接触,并在再次免疫中迅速做出应答
One kind of response is called the innate response and innate means that it's present from the beginning.
其中之一称为先天性免疫反应,先天的意思是生来就有的
But because of the similarity of the viruses, the immune response that people developed would also protect them against natural infections with variola.
因为这两种病毒很相像,人体的免疫应答也能保护自己,免受天花的感染
But innate responses are there from the very beginning and they can fight foreign--against foreign pathogens immediately.
但是先天免疫反应与生俱来,可以迅速同外源病原体展开斗争
It's simply your psychological immune system will become stronger, hopefully already by the end of this semester.
只是你的心理免疫系统会变得更强,希望在本学期未就见成效。
So, you couldn't introduce the live virus in because that would cause the disease not just immunity.
所以 不可以直接接种活体病毒,因为这会使人致病而不仅是引起免疫应答
That is, mix it with things which make it more make your immune system respond more strongly.
也就是说,增大剂量以使,你的免疫系统产生强烈的反应
How do you engineer what happens in our immune system in order to protect us from diseases?
我们如何将免疫功能工程化,保护我们远离疾病
Some, like the smallpox vaccine on one exposure generates a very high response that lasts for many years so you don't need a boost.
有一些疫苗,比如接触一次天花疫苗后,人体就能产生高水平的免疫应答,并持续很多年,所以无需再次接种
Now, why do you need a cell mediated immune response if you have an antibody response?
为什么你还要有细胞免疫反应呢,你已经有抗体应答了啊
Then, your muscle cells would start producing Hepatitis B surface antigen and your immune system recognizing that's a foreign protein would start responding to it.
于是,肌肉细胞将会,开始制造乙肝表面抗原,然后免疫系统就会识别出,那是外来蛋白质并且产生免疫应答
If you go onto study immunology you'll learn that this is one of the most important and rapidly evolving areas of the study of immunology.
如果你要继续学习免疫学的话,你就会知道这是免疫学中,最为重要而且高速发展的一个研究领域
You also mentioned vaccines and we're going to talk a lot in the middle part of the course about vaccines and the engineering of immunity.
你们也提到了疫苗,我们会在这学期重点讲它,疫苗以及免疫工程
And our psychological immune system strengthens when we give ourselves the permission to be human.
我们的心理免疫系统会加强,当我们准许自己为人时。
So, the antigen we're thinking about is a vaccine particularly designed to elicit immune response against a pathogen.
我们现在考虑的这种抗原,是一种特别设计的疫苗,它能够诱发免疫效应以消灭病原体
This is commonly used in the immune system as well, but it's a way of amplifying a signal.
免疫系统也常使用这种方法,但这主要是一种放大信号的方式
The immune system that we're used to thinking about is called the adaptive immune system, and the adaptive immune system does just that.
我们过去认识的免疫系统部分,现在被称为获得性免疫系统,获得性免疫系统功能如下
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