• So, there's no absolutes about this, this is a general response where all the features can be different with different pathogens.

    这其中并没有明确的规律,免疫应答是普遍存在的,但针对不同的病原体的应答规律各不相同

    耶鲁公开课 - 生物医学工程探索课程节选

  • When they do that they can actually engulf the bacteria in a process called phagocytosis and break them down into antigens.

    免疫细胞确实是将细菌整个吞进了肚内,这一过程称为吞噬作用,并将细菌分解成小抗原

    耶鲁公开课 - 生物医学工程探索课程节选

  • It's how quickly, how promptly we can recover from these painful emotions-- in other words, how strong our psychological immune system is.

    区别在于他们能够多么迅速,多么快速地从痛苦情绪中恢复过来-,换言之,我们的心理免疫系统有多强。

    哈佛公开课 - 幸福课课程节选

  • Suppose that most times and most activities were death free, but certain activities introduce the possibility of dying.

    假设大部分时间和大部分活动都是死亡免疫的,但某些活动,会引起死亡的可能性。

    耶鲁公开课 - 死亡课程节选

  • Humoral refers to immunity in the blood and it's immunity that's in the blood in the form of antibodies.

    体液免疫代表着血液中的免疫机制,血液中的免疫机制是以抗体的形式存在的

    耶鲁公开课 - 生物医学工程探索课程节选

  • So, just an introduction to the classes of potential foreign invaders that our immune system tries to defend us against.

    所以 我只是简单介绍几类,免疫系统试图抵御的潜在外来侵略者

    耶鲁公开课 - 生物医学工程探索课程节选

  • You don't have it, you don't have any immunity to smallpox, you don't have any reason to immunity to smallpox.

    你们对天花没有任何免疫力,你没有任何理由能对天花免疫

    耶鲁公开课 - 生物医学工程探索课程节选

  • We're going to talk about how they're prepared, but it's a preparation that is intended to stimulate your immune system.

    我们会讲它们是如何做准备的,它通过刺激你的免疫系统来进行准备

    耶鲁公开课 - 生物医学工程探索课程节选

  • This is a way for the immune system to recognize things that are going wrong inside the cell protected from antibodies.

    这是免疫系统识别,抗体不能识别的细胞内病变的方法

    耶鲁公开课 - 生物医学工程探索课程节选

  • In the immune system you could think of it as an even more complex set of outcomes that occur.

    免疫系统是一个,有更多复杂结果的大集合

    耶鲁公开课 - 生物医学工程探索课程节选

  • You've all been immunized for Hepatitis B, would you be happy to hear that that's where your Hepatitis B vaccine came from?

    你们都对乙型肝炎具有免疫力了,如果你知道你的乙型肝炎疫苗,是从何而来的话,你还会高兴的起来吗

    耶鲁公开课 - 生物医学工程探索课程节选

  • In fact, the people who have been most important in understanding how the innate immune system works are people here at Yale.

    事实上 在研究先天免疫系统,反应机理中,最重要的科学家就在耶鲁

    耶鲁公开课 - 生物医学工程探索课程节选

  • Usually it's done by taking all or part of the infectious agent, and showing them to your immune system in some way.

    通常它会带着全部或部分抗原介质,并以某种方式呈递给你的免疫系统

    耶鲁公开课 - 生物医学工程探索课程节选

  • Memory cells are long lasting cells that remember this exposure and can respond very quickly on second exposure.

    记忆细胞可以长时间记忆与抗原的接触,并在再次免疫中迅速做出应答

    耶鲁公开课 - 生物医学工程探索课程节选

  • One kind of response is called the innate response and innate means that it's present from the beginning.

    其中之一称为先天性免疫反应,先天的意思是生来就有的

    耶鲁公开课 - 生物医学工程探索课程节选

  • But because of the similarity of the viruses, the immune response that people developed would also protect them against natural infections with variola.

    因为这两种病毒很相像,人体的免疫应答也能保护自己,免受天花的感染

    耶鲁公开课 - 生物医学工程探索课程节选

  • But innate responses are there from the very beginning and they can fight foreign--against foreign pathogens immediately.

    但是先天免疫反应与生俱来,可以迅速同外源病原体展开斗争

    耶鲁公开课 - 生物医学工程探索课程节选

  • It's simply your psychological immune system will become stronger, hopefully already by the end of this semester.

    只是你的心理免疫系统会变得更强,希望在本学期未就见成效。

    哈佛公开课 - 幸福课课程节选

  • So, you couldn't introduce the live virus in because that would cause the disease not just immunity.

    所以 不可以直接接种活体病毒,因为这会使人致病而不仅是引起免疫应答

    耶鲁公开课 - 生物医学工程探索课程节选

  • That is, mix it with things which make it more make your immune system respond more strongly.

    也就是说,增大剂量以使,你的免疫系统产生强烈的反应

    耶鲁公开课 - 生物医学工程探索课程节选

  • How do you engineer what happens in our immune system in order to protect us from diseases?

    我们如何将免疫功能工程化,保护我们远离疾病

    耶鲁公开课 - 生物医学工程探索课程节选

  • Some, like the smallpox vaccine on one exposure generates a very high response that lasts for many years so you don't need a boost.

    有一些疫苗,比如接触一次天花疫苗后,人体就能产生高水平的免疫应答,并持续很多年,所以无需再次接种

    耶鲁公开课 - 生物医学工程探索课程节选

  • Now, why do you need a cell mediated immune response if you have an antibody response?

    为什么你还要有细胞免疫反应呢,你已经有抗体应答了啊

    耶鲁公开课 - 生物医学工程探索课程节选

  • Then, your muscle cells would start producing Hepatitis B surface antigen and your immune system recognizing that's a foreign protein would start responding to it.

    于是,肌肉细胞将会,开始制造乙肝表面抗原,然后免疫系统就会识别出,那是外来蛋白质并且产生免疫应答

    耶鲁公开课 - 生物医学工程探索课程节选

  • If you go onto study immunology you'll learn that this is one of the most important and rapidly evolving areas of the study of immunology.

    如果你要继续学习免疫学的话,你就会知道这是免疫学中,最为重要而且高速发展的一个研究领域

    耶鲁公开课 - 生物医学工程探索课程节选

  • You also mentioned vaccines and we're going to talk a lot in the middle part of the course about vaccines and the engineering of immunity.

    你们也提到了疫苗,我们会在这学期重点讲它,疫苗以及免疫工程

    耶鲁公开课 - 生物医学工程探索课程节选

  • And our psychological immune system strengthens when we give ourselves the permission to be human.

    我们的心理免疫系统会加强,当我们准许自己为人时。

    哈佛公开课 - 幸福课课程节选

  • So, the antigen we're thinking about is a vaccine particularly designed to elicit immune response against a pathogen.

    我们现在考虑的这种抗原,是一种特别设计的疫苗,它能够诱发免疫效应以消灭病原体

    耶鲁公开课 - 生物医学工程探索课程节选

  • This is commonly used in the immune system as well, but it's a way of amplifying a signal.

    免疫系统也常使用这种方法,但这主要是一种放大信号的方式

    耶鲁公开课 - 生物医学工程探索课程节选

  • The immune system that we're used to thinking about is called the adaptive immune system, and the adaptive immune system does just that.

    我们过去认识的免疫系统部分,现在被称为获得性免疫系统,获得性免疫系统功能如下

    耶鲁公开课 - 生物医学工程探索课程节选

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