"That's a preliminary communication, meaning we don't quite know the answer yet, but boy it looks like we are on to something big."

VOA: standard.2010.03.25

And actually, a question that might come up, I just explained, the sodium channel, you might say, well, how do potassium channels work then, because I can understand how you can filter something big out, but how do you filter out something small.

实际上，可能大家会问一个问题，我刚解释过，钠离子通道，你可以说，好吧，那么钾离子通道该如何起作用呢，因为我可以理解你是如何把大东西过滤掉的，但是你如何把小东西过滤掉呢？

麻省理工公开课 - 化学原理课程节选

it's not a really big event here, but it's still something cool.

返校日在这里不算是大活动，但是还是很酷。

对于返校日 - SpeakingMax英语口语达人

He says big coffee sellers like Starbucks help his business by building a base of customers who want something better.

VOA: special.2011.02.11

The trouble is, you just don't know when that explosion took place, and since there are several periods in this general area that we're talking about now, in which something big happened, some great change takes place, it turns out different people want to have their explosion at different times.

问题是,你不了解火山爆发的,确切时间以及这种爆发,在这个区域又延续了很多个时期,这些时期发生了许多重大事件和重大变化,结果就是不同人对,火山爆发的时间推测各不相同

耶鲁公开课 - 古希腊历史简介课程节选

"The mainstream media does not usually cover poverty or homelessness too much, unless someone dies or there's a big rally or something."

VOA: special.2011.02.25

And that's when, if you had everybody come to the theater for a big debate about something, you could still have people voting on certain things that the city might decide to do, although they couldn't rule themselves completely by themselves.

所以当时，如果所有人到剧院,对某一问题进行辩论，还是可以通过投票,决定某些事情，虽然他们无法进行完全的民主统治。

耶鲁公开课 - 新约课程节选

but for his 'big score,' Cobb is trying something new: "Inception."

VOA: standard.2010.07.16

That's a big issue. You can fix one thing, you break something else.

你可以解决一个问题，但你破坏了其它的程序。

麻省理工公开课 - 计算机科学及编程导论课程节选

It has to be something really big.

但必须是很重大的帮助。

哈佛公开课 - 幸福课课程节选

So, that is something these writers share with modernism, but there is one big difference and I want to exemplify that for you just by reading to you two parallel texts, one from the modernist canon and one from the Beat canon.

所以，这就是这些作者和现代主义的相似之处，但其中有个很大的区别，我想通过举例来说明,我给你们读两段类似的文字，分别是标准的现代主义风格和垮掉的一代的风格。

耶鲁公开课 - 1945年后的美国小说课程节选

So, you would expect that when you rip open the skull and look at the brain; you'd see something glorious, you'd see, I don't know a big, shiny thing with glass tubes and blinding lights and sparks and wonderful colors.

所以你会期待,当你打开头盖骨时,当你看到大脑的时候,你会看到些非常辉煌的东西,你会看见,我不知道,附有玻璃管的大块发光的东西,发出耀眼的光芒,不停地冒着火花,拥有美妙的颜色

耶鲁公开课 - 心理学导论课程节选

by luck or by inside information or by something, while there's sort of a big academic debate.

单纯的用运气或者内幕消息或者其他东西来解释，尽管对此学术界也存在着极大的争论。

耶鲁公开课 - 金融市场课程节选

And he's talking with Mississippi Gene. This is at the bottom of 26: There is something so indubitably reminiscent of Big Slim Hazard in Mississippi Gene's demeanor that I said, "Do you happen to have met a fellow called Big Slim Hazard somewhere?"

他在和密西西比的吉恩讲话，在26页下面：,现在，密西西比的吉恩的行为举止有些地方真切地,让我想起关于细杆的哈查德的往事，我问：“你是否在那里碰巧遇到过一个叫细杆哈查德的人“

耶鲁公开课 - 1945年后的美国小说课程节选

If n is something like 50, not a big number, 2 to the 50 is a huge number.

如果n是50，50不是一个大数，但2的50次方就是一个巨大的数。

麻省理工公开课 - 计算机科学及编程导论课程节选

You know, let's let some people make big fortunes because that provides spice in life and some adventure, something to look forward to-- that you might get this.

也可以让一部分人先富起来,富有带来更多的生活情趣,更多冒险，更多某些值得期待的东西-,有人会这么想。

耶鲁公开课 - 金融市场课程节选

I always worry about people who have such important businesses because some big deal may become in crisis or something; people like that have trouble sometimes adhering to a schedule.

我时常担心,这些人事务缠身,可能会因为某些突发的危机或别的事情,而改变自己的日程

耶鲁公开课 - 金融市场课程节选