It can be a small or large opening that reaches up to the nose.

VOA: special.2009.12.22

So, even if the cost is small, $10 a dose, it quickly amounts to a large amount of money.

因此,即使单只成本很小,可能只有十美元,但是这很快就会累积成为很大的金额

耶鲁公开课 - 生物医学工程探索课程节选

Small-cap stocks are tougher to price than large-cap stocks, so there's a 4.7% differential, first to third quartile.

小盘股比大盘股更难定价,第一和第三个四分位数的差距有4.7%

耶鲁公开课 - 金融市场课程节选

He struggled as a small businessman to compete with the large oil companies.

VOA: special.2010.04.25

You know, my experience with this is, when you go from having a small number to a really large number of people, if you don't a process, it becomes real chaos.

我的经验是，公司的员工由很少,增长到很多，如果没有一个程序，很容易乱套。

斯坦福公开课 - 戴尔CEO-Michael.Dell谈创业和发展课程节选

Barbancourt is small compared to large rum manufacturers like Bacardi, but the award winning spirit has an international circle of loyal fans.

VOA: standard.2010.06.01

One way to think about this intuitively if the derivative is very large the function is changing quickly, and therefore we want to take small steps.

关于这个方法很直观的一点想法是,如果导数非常大,函数也就变化的非常快，因此我们想一小步一小步的来。

麻省理工公开课 - 计算机科学及编程导论课程节选

The FAO report points to the growth of large-scale, industrial operations that have pushed some small producers and pastoralists to the margins.

VOA: standard.2010.02.22

What used to be a large french fry at McDonald's is now the small French fries and so a lot of people will order something, like they'll go to a restaurant and they'll say, well would you like small, medium or large?

现在小包的麦当劳薯条,过去曾是被叫做大包,所以当人们走进饭店,点餐的时候营业员问,你想要小包中包还是大包的薯条

耶鲁公开课 - 关于食物的心理学、生物学和政治学课程节选

The president says the bill will subject large and small banks to tougher oversight, and prevent banks from taking so much risk they could collapse and threaten the economy.

VOA: standard.2010.05.15

So the DNA is going to get spread out on this gel according to size, with the small ones going farther and the large ones not going as far.

因此DNA会根据大小,在凝胶上分散开,小的片段会快一些,大的片段不那么快

耶鲁公开课 - 生物医学工程探索课程节选

Despite signs of a gradually improving economy, job growth continues to lag in the U.S.Unemployment remains high at 10 percent after the economy shed another U.S.Chamber of Commerce President Thomas Donohue says the reason is obvious: uncertainty is causing large and small businesses to think twice before hiring new workers.

VOA: standard.2010.01.12