In the presence of this ligand, this molecule, it's open, it allows transport of this ion, when the ligand is gone it doesn't.

配体存在的情况下通道才打开,允许这些离子穿过,配体离开后,这些离子就不能通过了

耶鲁公开课 - 生物医学工程探索课程节选

He says these have been carried out in public, he has gone around in the market and in the open and in the public forum questioning, interrogating and obviously making a variety of people look foolish.

他说这些都是公开进行的，他游走在市集,在公开,及公共的论坛，提问，质问,且明显地让任何人难堪。

耶鲁公开课 - 政治哲学导论课程节选