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Drayna says therapies to replace enzymes that cause the diseases have been developed to treat half a dozen of these metabolic disorders.
VOA: standard.2010.02.11
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They often involve networks of reactions, not just one enzyme but a series of enzymes that serve to amplify each other.
这些反应通常包括一个反应网络,不只是一种酶,而是一系列的酶来进行级联放大
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That's an example of symmetric sequence and it happens that most restriction enzymes also recognize those spaces.
这是一个对称序列的例子,大多数限制性内切酶都能识别这些序列
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Enzymes, thyroid, etc., the abs, the serotonin, you can pick some part of the body.
比如,酶,甲状腺素等等,还有生物素,血清素,你也可以选择身体的某一部位来写
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Because that's the temperature at which many of the molecules in our bodies operate at their most efficient, and enzymes is the best example of that.
因为在正常体温下,体内许多分子活性最高,酶就是其中最好的例子
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They do that in a very special way in that they - restriction enzymes are able to identify a particular sequence of bases in a gene.
限制性内切酶的工作机制很特别,它能识别基因中的一段特定的碱基序列
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This takes advantage of the very specific properties of restriction enzymes.
这利用了限制酶的独特性质
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Enzymes work best, enzymes are proteins that catalyze chemical reactions and our bodies operate by elaborate networks of chemical reactions, When we're off from that temperature then they don't work properly.
举酶这个例子再好不过,酶是一种具有催化作用的蛋白质,人体依靠精密复杂的化学反应网络来运转,如果我们体温与之相差较大,这些酶就不能正常工作
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What are the properties of this restriction enzymes?
这种限制性内切酶的特性是什么
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There's whole families of restriction enzymes.
限制性内切酶是一个大家族
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It takes advantage of the specificity of the restriction enzymes, the fact that we know what the gene sequence that we're looking for, and using this technological process of electrophoresis to identify changes that we predict.
这个方法利用了限制酶特有的性质,我们知道我们在找什么样的基因序列,从而才能利用电泳这个技术流程,来识别出我们预计的情况
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When it cuts it leaves sticky ends or un-base paired single stranded regions on each end of the part its cut and that's just a property of many restriction enzymes; not all, some cut blunt,just right down the middle.
它切割后会留下两个粘性末端,或者未配对的单链部分,这是许多限制性内切酶的特性,但不是全部,有些限制性内切酶是从中间钝切的
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Now another property of restriction enzymes is that they always cut the DNA in the same way.
限制性内切酶的另一个特性是,总是以同样的方式切割DNA
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One of the enzymes that often gets activated is an enzyme which converts ATP, a small molecule that is inside all of our cells.
在经常被激活的酶中有一种酶,其功能是转化ATP,ATP是一种,存在于所有细胞中的小分子物质
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Restriction enzymes are just a kind of enzyme, enzymes are protein molecules that make a chemical reaction go faster, and the chemical reaction that restriction enzymes do is cutting DNA.
限制性内切酶是一种酶,而酶是加速化学反应的蛋白质分子,限制性内切酶加速的化学反应,是切割DNA
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That RNA is made into proteins, and proteins are the working molecules of the cell, they're enzymes, they're structural molecules, they're are proteins that exist in the membrane that allow things to go in and out of the cell, so really the working molecules are the cell in every sense.
这些RNA指导合成蛋白质,蛋白质是细胞生命活动的承担者,它们可以是酶,或是结构性分子,也可以存在于细胞膜上的膜蛋白,能够让一些物质通过它们进出于细胞,所以蛋白质才是真正意义上,细胞生命活动的承担者
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