Some want an independent review. And the trial's researchers, like Dr.Nelson Michael, of the Walter Reed Institute of Research in the United States, say it's unclear what difference the findings will make for areas like Africa where rates of HIV/AIDS are much higher than among the test population and where there are many strains of the virus.

VOA: standard.2009.10.20

Now this is a very striking visual display of how much difference an environment can make.

这短片给我们带来了震撼的直观感受,看到环境到底有多大的影响力

耶鲁公开课 - 关于食物的心理学、生物学和政治学课程节选

This doesn't seem to make much of a difference in language learning.

看起来这对语言学习没什么太大的影响

耶鲁公开课 - 心理学导论课程节选

You can't think that it really could make so much difference in the real world how prices and quantitie and welfare, and profit is going to work out depending on some thought experiment about how I think about my strategy set.

你们很难想象在现实世界里,价格 产量 福利和利润会因为,不同策略集合设定下的思想实验,而产生如此巨大的变化

耶鲁公开课 - 博弈论课程节选