So doctors must use stronger, "second line" drugs when the first ones fail.

VOA: special.2009.03.25

"So I think they get more nervous. When I am climbing out the window to climb on a ledge, the first ones go, 'Whoa,whoa,whoa,wait!'

VOA: standard.2010.07.26

We did make errors, but we had a lot of fun doing it. Being the first ones to do something that gigantic was very exciting."

VOA: standard.2009.08.14

"Parents and caregivers; the family members are the first ones who introduce vocabulary.

VOA: standard.2010.05.05

"We honor the women who traveled those lonely roads to be the first ones in those court rooms, to be the first ones in those board rooms, to be the first ones on those playing fields, and to be the first ones on those battlefields.

VOA: standard.2010.03.08