They're everywhere in cells throughout your body and they are responsible for lots of the biochemistry of cell/cell interaction and signaling.

它们在身体各处的细胞中都有,并负责很多细胞间的相互作用,及信号转导的生化过程

耶鲁公开课 - 生物医学工程探索课程节选

One example, on some of their biochemistry applications is with another Professor at MIT, Alice Ting and her lab.

和另外一个MIT的,教授Alice，Ting及她的,实验室在生化应用上展开合作。

麻省理工公开课 - 化学原理课程节选

And who, where would--If it was, if it was converted into a weapon, where would the vaccines to protect the rest of the country come from?

如果天花被转化成生化武器,去哪里才能找来保护国家的疫苗呢

耶鲁公开课 - 生物医学工程探索课程节选

This in combination with the effects of aging and with genetic disposition in some instances, can cause a worldwide pandemic, and this is what we're currently experiencing.

某些场合中,衰退和生化影响,能引发全球性的大流行，这也是我们近来所见所闻。

斯坦福公开课 - 7个颠覆你思想的演讲课程节选

So, they bind to the receptor - they occupy the receptor so now the natural ligand can't enter it but they don't create the same sequence of biochemical events.

因此,它们与受体结合,它们占据了受体,这样配体就进不来了,但这种结合无法诱发,真正的配体所能诱发的生化反应

耶鲁公开课 - 生物医学工程探索课程节选

If you hear about signal transduction in biology, people that study signal transduction are studying just these things we talked about, how biochemical messages get transferred into cells and through cells.

如果你在生物学领域听到信号转导这个词,那么研究信号转导的人就是,在研究我刚才讲过的那些东西,生化信息如何传入细胞并传递至细胞各处

耶鲁公开课 - 生物医学工程探索课程节选

We talked about modern imaging methods and this is an example of an fMRI, a functional MRI; a map of the brain that not only shows you the anatomy of the brain but shows you something about the chemistry of what's going on inside.

我们还说到现代影像技术,这里是一幅脑部功能性磁共振成像图像,一种功能性的磁共振,图中不仅可以看到脑部解剖学图像,也可以看到一些脑内的生化过程

耶鲁公开课 - 生物医学工程探索课程节选

If that protein is an enzyme then you've and you've switched it from an 'off' position where it's not catalyzing a reaction to an 'on' position where it is, you've changed the biochemical state of the cell, you've changed the chemical reactions that can occur within the cell, and you've changed its behavior.

如果这种蛋白是一种酶的话,你就能够将酶从无催化作用的静息态,激活至能催化反应的激活态,你改变了细胞的生化状态,也改变了细胞内发生的化学反应,改变了细胞的行为

耶鲁公开课 - 生物医学工程探索课程节选

During the section times I'll be available if you feel like you want to read Chapters 2 and 4 and then come and ask questions, sort of a tutorial on these topics of chemistry and biochemistry, then I'll be available to talk about that during that time.

在小组讨论的时间里,你们可以来找我,如果你们学习完第二章和第四章之后,想问一些关于,化学和生化方面的问题,可以来找我,我会在那个时候给你们进行讲解

耶鲁公开课 - 生物医学工程探索课程节选

Insulin, the ligand binds to its receptor, creates a change through a kinase activity that's exposed, which leads to other biochemical changes, which leads to a change in cell behavior - in this case the cell behavior is that more glucose transporters are brought to the membrane and more glucose can enter the cell.

胰岛素,一种能够与受体结合的配体,通过其暴露出的激酶活性引起的变化,导致了其它后续生化变化的发生,进而使细胞行为发生改变,这个例子中的细胞行为就是,更多的糖载体被带到细胞膜表面,这样更多的糖分子进入到细胞内部

耶鲁公开课 - 生物医学工程探索课程节选

The G-protein then goes on to create some other biochemical changes inside the cell.

然后G蛋白在细胞内,诱发其它的一些生化反应

耶鲁公开课 - 生物医学工程探索课程节选