You need to be able to integrate that information into a response, and that happens through these biochemical reactions.

体内的细胞要整合信息并作出反应,这个过程就通过这些生化反应来完成

耶鲁公开课 - 生物医学工程探索课程节选

So, they bind to the receptor - they occupy the receptor so now the natural ligand can't enter it but they don't create the same sequence of biochemical events.

因此,它们与受体结合,它们占据了受体,这样配体就进不来了,但这种结合无法诱发,真正的配体所能诱发的生化反应

耶鲁公开课 - 生物医学工程探索课程节选

If that protein is an enzyme then you've and you've switched it from an 'off' position where it's not catalyzing a reaction to an 'on' position where it is, you've changed the biochemical state of the cell, you've changed the chemical reactions that can occur within the cell, and you've changed its behavior.

如果这种蛋白是一种酶的话,你就能够将酶从无催化作用的静息态,激活至能催化反应的激活态,你改变了细胞的生化状态,也改变了细胞内发生的化学反应,改变了细胞的行为

耶鲁公开课 - 生物医学工程探索课程节选

The G-protein then goes on to create some other biochemical changes inside the cell.

然后G蛋白在细胞内,诱发其它的一些生化反应

耶鲁公开课 - 生物医学工程探索课程节选