Smoking may suppress the expression of ERCC1 gene.
吸烟可抑制ERCC1基因的表达。
Objective: To study the effect on drug resistance by RNAi mediated ERCC1 gene silencing in ovarian cancer cell line.
目的：观察rna干扰沉默ercc1基因对卵巢癌细胞耐药的影响。
Conclusion Antisense ERCC1 RNA decreased the repair capability for damaged DNA in lung cancer cells induced by benzopyrene.
结论ERCC 1反义rna降低肺癌细胞对苯并(a)芘所致DNA损伤的修复能力。
Methods The expression of ERCC1, RRM1 and BRCA1 protein in 122 cases of advanced NSCLC was detected by immunohistochemical methods.
方法应用免疫组织化学方法对122例晚期NSCLC组织进行ERCC1、RRM1及BRCA1蛋白表达检测。
In one instance, the researchers at Duke even claimed that their work made biological sense based on the presence of a gene, called ercc1.
比如，杜克大学的研究员甚至声称，基于一个叫做ERCC1的基因的存在，他们的工作是具有生物学意义的。
Results: After transfection of the antisense ERCC1, Northern and Western blotting indicated that the RNA and protein expression level of ERCC1 was obviously decreased.
结果：卵巢癌细胞转染反义ERCC1基因后，ERCC1基因转录水平、蛋白表达水平明显下降。
AIM: To investigate the expression of nucleotide excision repair gene ERCC1 and its relationship with PAH (polycyclic aromatic hydrocarbons) -dna adducts in lung cancer tissues.
目的：探讨核苷酸切除修复基因ERCC1在肺癌中的表达及其与多环芳烃(PAH) -DNA加合物的关系。
Objective To investigate the expression of DNA repair gene family members of ERCC1, RRM1 and BRCA1 in tissues of advanced non-small cell lung cancer (NSCLC), and explore its clinical significance.
目的探讨晚期非小细胞肺癌(NSCLC)组织中DNA修复基因家族成员ERCC1、RRM1和BRCA1的表达及其临床意义。
Objective To investigate the expression of DNA repair gene family members of ERCC1, RRM1 and BRCA1 in tissues of advanced non-small cell lung cancer (NSCLC), and explore its clinical significance.
目的探讨晚期非小细胞肺癌(NSCLC)组织中DNA修复基因家族成员ERCC1、RRM1和BRCA1的表达及其临床意义。
应用推荐