Smoking may suppress the expression of ERCC1 gene.

吸烟可抑制ERCC1基因的表达。

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Objective: To study the effect on drug resistance by RNAi mediated ERCC1 gene silencing in ovarian cancer cell line.

目的：观察rna干扰沉默ercc1基因对卵巢癌细胞耐药的影响。

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Conclusion Antisense ERCC1 RNA decreased the repair capability for damaged DNA in lung cancer cells induced by benzopyrene.

结论ERCC 1反义rna降低肺癌细胞对苯并(a)芘所致DNA损伤的修复能力。

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