Heat shock protein(HSP) shows both biological effects of up-regulation and down-regulation on apoptosis. Especially the suppressive effects on apoptosis provide a new path to treat various diseases.
热休克蛋白（HSP）对细胞凋亡有双向调控作用，尤其是其抗细胞凋亡的作用为临床多种疾病的治疗开辟了新的途径。
Results The obtained results showed that 143 genes revealed up-regulation and 101 genes showed down-regulation.
结果研究发现有143条基因在给药组中发生上调，101条基因发生了下调。
Conclusion: The over-expression of IGF-1R and down-regulation of PTEN expression may play a role in pathologic scar.
结论：IGF - 1r的高表达和PTEN的表达下调在病理性瘢痕形成中起重要作用。
The rates of COMT gene expression down-regulation in OCD patients with OCPD and ones without OCPD were 14%and 56%respectively.
伴强迫人格与无强迫人格的强迫症患者COMT基因表达水平分别下调14%和56%；
There exist hypermethylation, abnormal transcription of FHIT gene and down-regulation expression of FHIT protein in liver cancer.
肝癌中存在FHIT基因高甲基化、转录异常、FHIT蛋白表达下降。
The mechanism of insulin-resistance is the down-regulation oftarget cells, which is a vital function of self-protection during stress.
胰岛素抵抗的原因在效应细胞受体下调，是机体应激时重要的自我保护手段。
AIM: To study the effects of down-regulation of guanine nucleotide exchange protein 100 (GEP100) on the invasive ability of pancreatic cancer cell AsPC-1 in vitro.
目的：研究鸟嘌呤核苷酸交换蛋白100 (GEP100)基因沉默对胰腺癌细胞体外侵袭能力的影响。
Conclusion Neoadjuvant chemotherapy with ET regimen is effective, and it may inhibit the proliferation of breast cancer cell by down-regulation of the expression of MCM7.
结论ET方案新辅助化疗有较好的疗效，可能通过抑制MCM 7蛋白的表达来阻止乳腺癌细胞的增殖。
Conclusion: The increased IMT might be related with down-regulation of complement regulatory protein CD55 expression, but has no direct association with complement C3, C4, properdin and CD59.
结论：颈动脉imt增厚与补体调节蛋白CD 55表达降低相关，而与补体C 3、C4、备解素、补体调节蛋白CD 59无直接关系。
It is possible that glucocorticoid receptor down-regulation indicates disorders of stress response and also may be associated with altered immune status of patients with ACLF of different stages.
糖皮质激素受体的下调提示可能与患者机体应激反应紊乱，以及肝衰竭不同时期免疫状态的改变有关。
Down-regulation of E-CD expression and high expression of CD44 were correlated with enterocelia spread of ovarian cancers.
卵巢癌组织及大网膜转移灶组织E CD表达下调及CD44表达增强与卵巢癌腹腔播散密切相关。
Two major attempts at regulation have been struck down by the courts, either in whole or in part.
两种主要的在制定规则方面的尝试已经全部或者部分地被法院否决了。
Results 16 identified genes expressed differently, including 13 down-regulated in which 4 were related to endocrine regulation.
结果芯片结果显示实验组已知功能差异表达基因有16条。其中下调基因有13条，4条与内分泌调控密切相关。
The overlap of salt and drought stress regulation network shows that degradation-related pathways were down-regulated by the AGL15, ARR10.
在盐和干旱胁迫下的共调控网络中，转录因子AGL15和ARR10下调降解相关的代谢途径。
Certain coal fire power stations are due to shut down in various member states due to new regulation.
根据最新欧盟法规，许多欧盟成员国将关闭某些燃煤发电站。
I think what it comes down to is a matter of licensing and a matter of regulation.
我认为，这最终会归结到许可证和规则的问题上来。
To reduce automobile emission pollution, many countries lay down emission control regulation of automobile diesel engine.
为减少汽车带来的排气污染，许多国家均对车用柴油机制定了相应的排放法规。
B: I'm sorry. Every customer coming here must do the warm-up exercise before getting down to swimming. That's out regulation.
对不起，任何一位到我们这来的顾客在下水游泳之前必须要做热身运动。这是我们的规定。
CONCLUSION: the results indicate that the mechanism of mesenteric lymph ligation alleviating the lung injury after shock is related to up or down regulation of the above genes.
结论：肠淋巴管结扎干预休克肺损伤的机制与上调或下调上述相关基因的表达有关。
The expression deficiency or down regulation of RUNX3 gene was detected in many malignant tumors especially in gastric cancer.
在人类多种恶性肿瘤尤其是胃癌中发现RUNX3基因表达缺失或下调。
Conclusion: XTTL Gel may alleviate bone cancer pain by inhibition of bone resorption and down regulation TRPV1 expression in the bone and hypothalamus.
结论：消痰通络凝胶可有效抑制骨癌痛，其治疗骨癌痛的机理可能与减少骨吸收、下调骨及下丘脑TRPV1的表达有关。
ConclusionATRA could inhibit proliferation of yolk sac tumor cell line, and down regulation of VEGF could be the inhibitory mechanism of ATRA on yolk sac tumor cell line in vitro.
结论全反式维甲酸可以抑制睾丸卵黄囊瘤细胞的增殖，抑制肿瘤增殖机制可能与下调VEGF的表达有关。
The study result can provide scientific basis for laying down management regulation on prawn drift net fishing gear in the Bobal Sea.
这项研究成果为制定渤海对虾流网渔业管理细则提供了科学依据。
The study result can provide scientific basis for laying down management regulation on prawn drift net fishing gear in the Bobal Sea.
这项研究成果为制定渤海对虾流网渔业管理细则提供了科学依据。
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