...变化对垂体脉冲式释放FSH和LH是极为重要的，它可以从两方面调节FSH、LH分泌，即升调节(up-regulation)和降调节(down-regulation)又称双相反应(diphasicreaction)。
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...其它包括Homo sapiens U5 snRNP-specific protein、116Kd(U5-116KD)mRNA、Myosin Ⅵ等;(2)1169个基因被抑制下调(down-regulation)。其中最受抑制基因的是:Aquaporin 6,kidney specific;其它包括Ribosomal protein S17;等。
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receptor down-regulation 受体减量调节 ; 受体下行调节 ; 受体向下调节 ; 受体下调
down regulation [生理] 减量调节 ; 向下调节 ; 受体下调
down-regulation of receptors 受体的向下调节 ; 受体的衰减性调节
up or down regulation 上调或下调
Pituitary down-regulation 垂体降调节
receptors down-regulation 受体下调
In conclusion, the down-regulation of FPG cut point for the diagnosis of IFG had its rationality.
综上所述，IFG诊断切点的下调具有合理性。
参考来源 - 糖尿病前期人群的特点及转归研究The down-regulation of HAb18G/CD147 was shown to result in the degradation of E-cadherin and disruption of cell-cell contacts.
下调HAb18G/CD147可以导致E-cadherin在24 hr后逐步降解,细胞间连接断裂。
参考来源 - 哺乳动物工程细胞悬浮适应—可贴壁亚群（HEK293ar）的获得及其抗失巢凋亡机制研究·2,447,543篇论文数据，部分数据来源于NoteExpress
N a decrease in sensitivity, through overexposure, to a drug or other chemical caused by a reduction in the number or density of receptors on cell surfaces 减量调节
There exist hypermethylation, abnormal transcription of FHIT gene and down-regulation expression of FHIT protein in liver cancer.
肝癌中存在FHIT基因高甲基化、转录异常、FHIT蛋白表达下降。
The mechanism of insulin-resistance is the down-regulation oftarget cells, which is a vital function of self-protection during stress.
胰岛素抵抗的原因在效应细胞受体下调，是机体应激时重要的自我保护手段。
Conclusion: The increased IMT might be related with down-regulation of complement regulatory protein CD55 expression, but has no direct association with complement C3, C4, properdin and CD59.
结论：颈动脉imt增厚与补体调节蛋白CD 55表达降低相关，而与补体C 3、C4、备解素、补体调节蛋白CD 59无直接关系。
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