• CCR5 protein coverage in the major T-cell surface.

    CCR5蛋白质主要覆盖T细胞表面

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  • This variability means that a small deletion on the CCR5 gene.

    这种变异CCR5基因一小段缺失

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  • CCR5 protein coverage in the major T-cell surface, is a receptor protein.

    CCR5蛋白质主要覆盖T细胞表面一种蛋白受体

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  • CCR5, one of the coreceptors of HIV?1, is a new target of anti-HIV therapy.

    趋化因子受体CCR5HIV?1 进入靶细胞辅助受体,因而成为开发抗艾滋病药物的靶点。

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  • As a result, and in the fight against AIDS, CCR5 has played a crucial role.

    因此艾滋病斗争中,CCR5起到极为关键的作用。

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  • Other researchers are experimenting with gene therapy to fully prevent the emergence of CCR5.

    其他研究人员正在试验基因疗法完全阻止CCR5产生

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  • Results Compared to B6 WT group, B6 CCR5 KO group succumbed to acute GVHD at an accelerated rate.

    结果B6WT比较,B6CCR5KO组小鼠以更快的速度于急性移植物抗宿主疾病(GVHD);

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  • Without CCR5 for the HIV to rob, the patient's immune cells can effectively resist HIV and prevent infection.

    如果没有CCR5艾滋病毒的“抢劫”,病人免疫细胞有效地抵抗艾滋病毒防止其感染发生

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  • Since the virus can't gain a foothold on cells that lack CCR5, people who have the mutation have natural protection.

    如果细胞没有足够的CCR 5, HIV病毒就无法细胞上立足,所以发生这种突变的自然可以受到保护。

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  • The mutation is known as CCR5 delta32 and is found in 1 percent to 3 percent of white populations of European descent.

    这种CCR5delta32的基因突变在欧洲的白人中的存在概率为1%3%。

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  • Moreover, people found in HIV disease progression, CCR5-preferring viruses would transform into CXCR4-preferring ones.

    人们还发现HIV感染疾病进展中存在嗜ccr5病毒株向嗜cxcr4毒株的转化

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  • Objective To investigate the role of CC chemokine receptor 5(CCR5) in the immunological pathogenesis of hepatitis B(HB). ?

    目的研究细胞趋化因子受体5CCR5乙型病毒性肝炎(HB)免疫发病机制中的作用

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  • HIV USES the CCR5 as a co-receptor (in addition to CD4 receptors) to latch on to and ultimately destroy immune system cells.

    HIV利用CCR5受体(除此之外还有CD 4受体)最终破坏免疫系统细胞

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  • The latter experiments also identified the cells on which CCR1 and CCR5 expression is important for promoting liver fibrosis.

    最近实验表明表面有CCR1CCR5表达细胞促进纤维化重要作用。

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  • In the recent years, the research of HIV-1 infecting immunocytes by chemokine receptor CCR5 and CXCR4 was caused more attention.

    近年来,HIV - 1借助趋化因子受体(C CR 5,CXCR4)感染免疫细胞方面研究引起了广泛关注。

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  • The CCR5 ribozyme molecule stops the patient's white blood cells producing CCR5, a protein that HIV USES to get into host cells.

    这种CCR5核酶分子能中止病人血细胞产生CCR5,后者艾滋病毒用于进入宿主细胞一种蛋白质

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  • Objective: to study the relation of RANTES and its receptor (CCR5) expression in gastric cancer and in lymph nodes with cancer metastasis.

    目的探讨RANTES及其受体(CCR5)胃癌转移淋巴结组织中的表达及其胃癌转移关系

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  • This patient's own cells had the usual amount of the CCR5 receptor, and the strain of HIV in his blood was the type that used the receptor.

    回到这个研究中,这个患者存在着正常CCR5基因,同时感染病毒利用这个基因复制HIV

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  • All of these biological effects are performed by binding of ligands to receptors. Elsewhere, CXCR3 and CCR5 are mark chemokine receptors in RA.

    它们这些生物学功能通过配体受体结合的方式来发挥的,而CXCR3CCR5是RA中趋化因子的标志性受体。

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  • Furthermore, expression of both CCR2 and CCR5 genes was enhanced significantly in activated macrophages when compared with non-activated macrophages.

    而且激活细胞比较,已经 激活的巨噬细胞CCR2CCR5基因表达增强更为明显

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  • CCR5, a membrane protein on cell surface, is a member of the G protein-coupled receptor superfamily and one of the major co-receptors for HIV-1infection.

    CCR5细胞膜蛋白,属于G蛋白偶联受体家族成员HIV - 1入侵机体细胞的主要辅助受体之一。

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  • Conclusion The recombinant adenovirus carrying antisense RNA to CCR5 has laid down a good foundation for studying its inhibiting effect on HIV-1 infection.

    结论成功地构建了携带CCR5反义rna重组腺病毒载体研究hiv 1的作用打下基础

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  • Conclusion the expression of CCR5 is significantly correlated with the immune system reaction toward HIV and disease progression in HIV-1 infected patients.

    结论HIV 1感染者第二受体ccr5表达机体HIV免疫反应疾病进展密切相关。

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  • Conclusion Expression levels of peripheral blood CD4 + t lymphocytes surface CCR5 may be closely related to the susceptibility to HIV infection and the disease progression.

    结论此项研究表明外周血CD 4 +T淋巴细胞表面CCR5表达差异与HIV易感性疾病进展情况密切相关。

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  • If the mutation, called Delta 32, is inherited from both parents, it prevents HIV from attaching itself to cells by blocking CCR5, a receptor that ACTS as a kind of gateway.

    假设父母遗传基因突变称作Delta32通过阻断CCR5来阻止HIV附着细胞上,CCR5是一通道受体

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  • Before undergoing the transplant, the patient was also found to be infected with low levels of a type of HIV known as X4, which does not use the CCR5 receptor to infect cells.

    进行移植病人发现感染了少量HIV病毒,X4这种病毒利用CCR5作为受体感染细胞。

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  • Histological assessment of the mice indicated pathological lesions in the kidneys and a greater degree of liver pathological changes in mice that received CCR5 KO donor grafts.

    组织学评价提示移植剔除CCR5基因受者细胞小鼠肾脏出现病理损伤并且肝脏存在有更为严重的病理变化

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  • Histological assessment of the mice indicated pathological lesions in the kidneys and a greater degree of liver pathological changes in mice that received CCR5 KO donor grafts.

    组织学评价提示移植剔除CCR5基因受者细胞小鼠肾脏出现病理损伤并且肝脏存在有更为严重的病理变化

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