Objective To investigate thiopurine methyltransferase(TPMT) activity distribution in Chinese Han and Yao population.
目的研究巯基嘌呤甲基转移酶（TPMT）活性在中国汉族和瑶族人群中的分布。
TPMT genotype correlates well with in vivo enzyme activity in erythrocytes and is closely associated with risk of toxicity. Genetic mutations are responsible for TPMT deficiency.
TPMT活性具有遗传多态性和种族差异。 TPMT酶活性降低或缺乏与其基因突变密切相关。
TPMT genotype correlates well with in vivo enzyme activity in erythrocytes and is closely associated with risk of toxicity. Genetic mutations are responsible for TPMT deficiency.
TPMT活性具有遗传多态性和种族差异。 TPMT酶活性降低或缺乏与其基因突变密切相关。
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