The maximum tolerated dose? The minimum dose that leads to maximum inhibition of the target?
但什么是这些药物的最佳剂量，最大耐受剂量，最大限度抑制目标的最小剂量？
The researchers hae not reached the maximum tolerated dose yet and are continuing to enrol new patients.
研究者还没有找到最大的耐受量，现在正招募新的病人。
The researchers have not reached the maximum tolerated dose yet and are continuing to enrol new patients.
研究者还没有找到最大的耐受量，现在正招募新的病人。
In this paper, the estimation of the maximum tolerated dose of a drug for phase I clinical trials is investigated.
这篇论文主要研究的是第i阶段临床试验中最大耐受剂量的估计问题。
The paper investigates designs of dose-finding trials, the purpose of which is to determine the maximum tolerated dose (MTD).
本文研究的是药物最大耐受剂量（MTD）的识别方法。
It mainly introduces different, methods about determining maximum tolerated dose (MTD) and proposes further subjects for future research.
主要介绍确定最大耐受剂量(MTD)的不同方法，以及提出可以进一步进行研究的问题。
This paper summarizes studies for phase I clinical trials. It mainly introduces different, methods about determining maximum tolerated dose(MTD) and proposes further subjects for future research.
本文综述关于I期临床试验的研究。主要介绍确定最大耐受剂量（MTD）的不同方法，以及提出可以进一步进行研究的问题。
All dose levels were well tolerated, with patients experiencing only mild side effects, such as flu-like symptoms.
所有剂量水平的治疗均处于可接受范围内，病人仅出现轻微的副作用，比如流感样症状。
At the proposed starting dose of 5 grams, the drug was found to be generally well tolerated with side effects that were mild to moderate.
推荐的首剂量是5克时，发现药物耐受性普遍良好，副作用从轻度到中度不等。
Patients in the high-dose group received perindopril at low dosage initially and gradually increasing to the high dosage and tolerated well.
较大剂量组患者采用小剂量逐渐递增剂量方式给药，且耐受性良好。
HCV-796 was found to be generally well tolerated, with favorable pharmacokinetics and no dose-limiting toxicities.
HCV- 796被发现通常很好地被宽容，借由有利的药物动力学和没有剂量限值毒性。
HCV-796 was found to be generally well tolerated, with favorable pharmacokinetics and no dose-limiting toxicities.
HCV- 796被发现通常很好地被宽容，借由有利的药物动力学和没有剂量限值毒性。
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