The researchers have not reached the maximum tolerated dose yet and are continuing to enrol new patients.

研究者还没有找到最大的耐受量，现在正招募新的病人。

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The paper investigates designs of dose-finding trials, the purpose of which is to determine the maximum tolerated dose (MTD).

本文研究的是药物最大耐受剂量（MTD）的识别方法。

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This paper summarizes studies for phase I clinical trials. It mainly introduces different, methods about determining maximum tolerated dose(MTD) and proposes further subjects for future research.

本文综述关于I期临床试验的研究。主要介绍确定最大耐受剂量（MTD）的不同方法，以及提出可以进一步进行研究的问题。

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During the first ten weeks of their treatment each was either given Mirapex or levadopa at the maximum tolerated dose.

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Targretin is generally used at the highest tolerated dose in cancer patients, according to Keith Flaherty, a skin-cancer specialist at Harvard Medical School.

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