• Methods Co culture systems of RPE cells with antigen specific t lymphocyte lines and resting t lymphocytes were established in vitro.

    方法建立RPE抗原特异性T淋巴细胞系静止淋巴细胞之间培养系统

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  • T cell can only recognize specific antigenic peptide-MHC complex on antigen-presenting cell. This is MHC restriction in antigen recognition of t cell.

    细胞只能识别抗原提呈细胞表面特定抗原MHC分子复合物,就是T细胞抗原识别MHC限制

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  • It has been proved that Dendritic cells (DCs) have strongly ability to present antigen. DCs can trigger t cell responses and enhance the t cell mediated anti tumor effect.

    树状细胞(DC)具有强大抗原递呈能力,并有效激发T细胞应答,是目前肿瘤免疫治疗研究的热点之一。

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  • The first signal is the binding of antigen with TCR on T cells. The second signal is the binding of co-stimulate on the APC with their receptors presenting on T and B lymphocytes.

    第一信号抗原T细胞受体TCR结合第二信号为抗原递呈细胞的协同刺激分子与TB淋巴细胞上的受体结合。

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  • Objective To establish long-term cultured antigen-specific T cell line and clones and to analyze their T cell receptor usage.

    目的体外建立长期培养抗原特异性T细胞系克隆并分析T细胞受体使用情况

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  • Unfortunately for the virus, t antigen also serves as a target for immune (t) cells, which can destroy infected cells and prevent the virus from spreading.

    对于这种病毒来说不幸的是,T抗原同样也是免疫(t)细胞攻击对象,也就是说,免疫细胞将摧毁受到感染的细胞来防止病毒进一步扩展。

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  • It is assumed that the reason resulting in such change is either t cell maturation of the down regulation of t cell antigen receptors.

    推测造成这种T细胞亚群变化原因可能T细胞发育成熟及T细胞本身的调节有关

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  • Conveniently, the microRNA that targets t antigen is made late in the infectious cycle, just when t antigen is no longer essential for virus replication.

    t抗原攻击目标的分子rna感染周期的最后环节才会产生,而这时t抗原已经不再是病毒繁殖的必须条件

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  • METHODS The T-antigen monoclonal antibody method and the galactose oxidase method were simultaneously used to detect T-antigen in large intestinal mucus of 207 cases.

    方法同时采用T抗原单克隆抗体乳糖氧化酶检测207例直肠粘液中的T抗原。

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  • Results Autologous t lymphocytes induced by DCs pulsed with myeloma lysates had stronger killing effect on myeloma cells than t lymphocytes induced by non myeloma antigen pulsed DC.

    结果骨髓瘤冻融DC诱导自身T细胞患者骨髓瘤细胞杀伤率远大于致敏dc

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  • Results Autologous t lymphocytes induced by DCs pulsed with myeloma lysates had stronger killing effect on myeloma cells than t lymphocytes induced by non myeloma antigen pulsed DC.

    结果骨髓瘤冻融DC诱导自身T细胞患者骨髓瘤细胞杀伤率远大于致敏dc

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