To study the expression of PLK1 and PCNA in breast carcinoma and its clinical significance.
目的探讨乳腺癌组织中PLK1、增殖细胞核抗原(pcna)的表达及其临床意义。
Conclusion: Evodiamine could inhibit invasion of human gastric carcinoma cell through down regulating of PLK1 expression.
结论：吴茱萸碱可明显抑制胃癌细胞侵袭力，其机制可能与下调PLK1基因表达有关。
The silencing RNA seeks out and binds to the RNA for a specific cancer-causing protein, called PLK1, and tags it for destruction.
沉默RNA搜出用于翻译特异性引发癌症的蛋白即PLK1的RNA，并与之结合，破坏癌细胞。
In addition, while DNA damage has been found to inhibit PLK1 kinase activity, the Thr210Asp mutant is resistant to this inhibition (13).
另外，尽管DNA损伤被发现能够抑制PLK1激酶活性，苏氨酸(210位)被天冬氨酸取代后能够抵制这种抑制作用(13)。
In addition, while DNA damage has been found to inhibit PLK1 kinase activity, the Thr210Asp mutant is resistant to this inhibition (13).
另外，尽管DNA损伤被发现能够抑制PLK1激酶活性，苏氨酸(210位)被天冬氨酸取代后能够抵制这种抑制作用(13)。
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