Objective: To explore the first-pass effect in Small intestine.
目的：探讨小肠在首过效应中的作用。
ConclusionThe metabolism of DBDCT in rat liver microsomes was faster, suggesting that the liver first-pass effect of the drug may be stronger.
结论DBDCT在大鼠肝微粒体中代谢较快，提示该药可能肝首过效应较强。
Documents show that the low biological activity of quercetin is due to its low bioavailability. Poor solubility and first-pass effect are the main factors that affect its bioavailability.
文献表明槲皮素生物活性低是由于其低的生物利用度，溶解性差与首过效应是影响其生物利用度的主要因素。
Documents show that the low biological activity of quercetin is due to its low bioavailability. Poor solubility and first-pass effect are the main factors that affect its bioavailability.
文献表明槲皮素生物活性低是由于其低的生物利用度，溶解性差与首过效应是影响其生物利用度的主要因素。
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