P53 mutation was positively correlated with overexpression of p53 protein.
p53基因突变与p53蛋白过度表达呈正相关关系。
Acetylation appears to play a positive role in the accumulation of p53 protein in stress response (17).
乙酰化似乎对于应激反应中p 53蛋白的累积起着正向的作用(17)。
Acetylation appears to play a positive role in the accumulation of p53 protein in stress response (17).
在压力应激反应中乙酰化能够发挥促进p 53蛋白富集的作用(17)。
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser15 of mouse p53 protein.
单克隆抗体由合成肽段免疫动物产生，该肽段与小鼠p 53蛋白的15丝氨酸及其邻近氨基酸残基序列一致。
Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser15 of human p53 protein.
该单克隆抗体是由合成的人源的针对p 53蛋白丝氨酸(15位)的磷酸化肽段免疫动物生产的。
The P53 protein may act as the marker determining biological behaviors of gastric cancer.
P53蛋白可作为判断胃癌生物学行为的指标。
Objective To explore the significance of P53 protein expression in different type of thymoma.
目的探讨p53的表达在不同类型胸腺瘤中的意义。
Conclusion: P53 protein significantly inhibits telomerase activity in human keloid fibroblasts.
结论：P 53蛋白能够抑制人瘢痕疙瘩成纤维细胞端粒酶活性。
Objective: To study the relationship between smoking and P53 protein expression in oral tumor tissue.
目的：研究吸烟与口腔肿瘤组织中P53蛋白表达的关系，探讨吸烟致口腔癌的发病机制。
Objective: to study the histological features and expression of P53 protein of lung cancer in aged patients.
目的：研究老年肺癌组织学特点及其P 53蛋白的表达。
Objective: To explore the clinical significance of expressions of P53 protein and PCNA in gastric carcinoma.
目的：探讨P 53蛋白和PCNA在胃癌中的表达及其临床意义。
It is suggested that the overexpression of P53 protein may be an early event in carcinogenesis of the esophagus.
结果表明：P 53基因蛋白产物的高表达在食管癌的发生中是一个早期生物学标志。
The expression of P53 protein was associated with the degree of differentiation, but not with the tumor locus and metastasis.
P53蛋白在胆管癌中表达升高，其表达与胆管癌的分化程度有关而与肿瘤部位及有无转移无关。
Objective To explore the expression of CD105 protein in esophageal squamous cell carcinoma and it's relationship with P53 protein.
目的探讨CD 105蛋白在食管鳞状细胞癌（鳞癌）组织中的表达，及其与P 53蛋白表达的关系。
Conclusion: the peritumoral edema on MRI in supratentorial astrocytic gliomas can reflect the positive expression rate of P53 protein.
结论：幕上星形细胞瘤瘤周水肿MRI表现反映了肿瘤组织P 53蛋白的表达程度。
These results indicate that progression of enzootic bovine leucosis is closely related to expression of P53 protein in tumorous tissues.
提示，流行性牛白血病的发生与肿瘤组织中P 53蛋白表达有重要关系。
Objective To study the P53 protein expression and its diagnostic significance during the malignant transformation of gallbladder adenoma.
目的探讨胆囊腺瘤的癌变过程及P53的诊断价值。
Conclusion Downregulation of CGRP on the expression of P53 protein in ischemic neurons might promote the recovery of the ischemia neurons.
结论CGRP下调缺血神经元p 53蛋白的表达，可能对缺血神经元的恢复有促进作用。
But during the wound repairing, much less expression of PCNA and P53 protein in diabetic skin tissue compared with non-diabetic skin tissue.
而在创面组织修复过程中，糖尿病创面增殖细胞核抗原，P 53蛋白表达明显少于非糖尿病创面。
Objective: To study on the correlation between proliferating cell nucleus antigen (PCNA) and P53 protein expressions in ovarian epithelial tumors.
目的：研究卵巢上皮性肿瘤中pcna和P 53蛋白表达的相关性。
Conclusion: (1) P53 Protein detection, VEGF expression and IMVD can be Considered as a biological indicator of malignant Potential in tongue cancer.
结论：(1)P 53、VEGF的表达以及IMVD的测定可作为判断舌癌恶性潜能的重要生物学指标。
Objective To investigate the changes of the expression of CPP32 and P53 protein following neuronal cell injury after focal cerebral ischemia in rats.
目的探讨大鼠脑缺血后神经元损害过程中CPP32和P5 3蛋白表达的变化。
P53 protein expression was studied with immunohistochemically in 15normal oral mucosas, 45 precancerous lesions and 21 invasive squamous cell carcinomas.
用免疫组化技术检测了15例正常口腔粘膜、45例癌前病变和21例浸润性鳞癌标本的P53蛋白的表达。
No correlation was found between the P53 protein overexpression and the clinical stages, neck lymph node metastasis, local recurrence and, survival of LSCC.
P 53蛋白表达与喉癌临床分期、分型、颈淋巴转移、局部复发及预后无相关性。
Methods:Immunohistochemistry and PCR-SSCP were used to detect the expression of P53 protein and p53 gene mutation in 32 cases of TSCC and 10 cases of tongue leukoplakia.
方法：应用免疫组织化学和聚合酶链反应—单链构象多态性分析（PCR-SSCP）检测10例舌白斑和32例舌癌，并结合临床资料进行分析。
Objective To investigate the age-related changes of P53 protein expression in oral mucous membrane and their effects on pathogenesis of the oral precancerous lesions in elderly people.
目的研究正常口腔粘膜组织中P 5 3蛋白表达的增龄性变化，探讨上述变化在老年人口腔癌前损害发生过程中的作用。
The expression of mutation P53 protein was related closely to histopathologic grade, tumor size, metastasis and prognosis of tumor(P<0.05), but it was not related to histologic types(P>0.05).
P53蛋白的阳性表达与组织学分级、肿瘤预后复发及肿瘤大小关系密切（P＜0．05），但与组织学类型无相关性（P＞0．05）。
The expression of mutation P53 protein was related closely to histopathologic grade, tumor size, metastasis and prognosis of tumor(P<0.05), but it was not related to histologic types(P>0.05).
P53蛋白的阳性表达与组织学分级、肿瘤预后复发及肿瘤大小关系密切（P＜0．05），但与组织学类型无相关性（P＞0．05）。
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