P53 mutation was positively correlated with overexpression of p53 protein.
p53基因突变与p53蛋白过度表达呈正相关关系。
The p53 protein is arguably the most important sensor of stress that mammals possess.
对于p 53蛋白是哺乳动物最重要的应激传感器这一说法是由争议的。
The P53 protein may act as the marker determining biological behaviors of gastric cancer.
P53蛋白可作为判断胃癌生物学行为的指标。
Objective To explore the significance of P53 protein expression in different type of thymoma.
目的探讨p53的表达在不同类型胸腺瘤中的意义。
Conclusion: P53 protein significantly inhibits telomerase activity in human keloid fibroblasts.
结论：P 53蛋白能够抑制人瘢痕疙瘩成纤维细胞端粒酶活性。
Acetylation appears to play a positive role in the accumulation of p53 protein in stress response (17).
乙酰化似乎对于应激反应中p 53蛋白的累积起着正向的作用(17)。
Acetylation appears to play a positive role in the accumulation of p53 protein in stress response (17).
在压力应激反应中乙酰化能够发挥促进p 53蛋白富集的作用(17)。
Objective: to study the histological features and expression of P53 protein of lung cancer in aged patients.
目的：研究老年肺癌组织学特点及其P 53蛋白的表达。
Objective: To explore the clinical significance of expressions of P53 protein and PCNA in gastric carcinoma.
目的：探讨P 53蛋白和PCNA在胃癌中的表达及其临床意义。
It is suggested that the overexpression of P53 protein may be an early event in carcinogenesis of the esophagus.
结果表明：P 53基因蛋白产物的高表达在食管癌的发生中是一个早期生物学标志。
The expression of P53 protein was associated with the degree of differentiation, but not with the tumor locus and metastasis.
P53蛋白在胆管癌中表达升高，其表达与胆管癌的分化程度有关而与肿瘤部位及有无转移无关。
Objective To explore the expression of CD105 protein in esophageal squamous cell carcinoma and it's relationship with P53 protein.
目的探讨CD 105蛋白在食管鳞状细胞癌（鳞癌）组织中的表达，及其与P 53蛋白表达的关系。
Conclusion: the peritumoral edema on MRI in supratentorial astrocytic gliomas can reflect the positive expression rate of P53 protein.
结论：幕上星形细胞瘤瘤周水肿MRI表现反映了肿瘤组织P 53蛋白的表达程度。
These results indicate that progression of enzootic bovine leucosis is closely related to expression of P53 protein in tumorous tissues.
提示，流行性牛白血病的发生与肿瘤组织中P 53蛋白表达有重要关系。
Objective To study the P53 protein expression and its diagnostic significance during the malignant transformation of gallbladder adenoma.
目的探讨胆囊腺瘤的癌变过程及P53的诊断价值。
Conclusion Downregulation of CGRP on the expression of P53 protein in ischemic neurons might promote the recovery of the ischemia neurons.
结论CGRP下调缺血神经元p 53蛋白的表达，可能对缺血神经元的恢复有促进作用。
But during the wound repairing, much less expression of PCNA and P53 protein in diabetic skin tissue compared with non-diabetic skin tissue.
而在创面组织修复过程中，糖尿病创面增殖细胞核抗原，P 53蛋白表达明显少于非糖尿病创面。
Aim: Discuss the application value and possibility of serum level of P53 protein as a early monitoring marker to the occupational lung cancer.
目的：探讨血清p5 3蛋白作为职业性肺癌早期监测指标的可能性和应用价值。
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser15 of mouse p53 protein.
单克隆抗体由合成肽段免疫动物产生，该肽段与小鼠p 53蛋白的15丝氨酸及其邻近氨基酸残基序列一致。
Objective: To study on the correlation between proliferating cell nucleus antigen (PCNA) and P53 protein expressions in ovarian epithelial tumors.
目的：研究卵巢上皮性肿瘤中pcna和P 53蛋白表达的相关性。
Conclusion: P53 protein can be used in early clinical diagnosis. Early in gastric carcinogenesis, its change occurs at intestinal metaplasia stage.
结论：p 53蛋白可在胃癌的早期诊断中起作用，其改变在胃癌发生的早期即居于肠化生阶段的癌前变化过程中。
Conclusion: (1) P53 Protein detection, VEGF expression and IMVD can be Considered as a biological indicator of malignant Potential in tongue cancer.
结论：(1)P 53、VEGF的表达以及IMVD的测定可作为判断舌癌恶性潜能的重要生物学指标。
Objective To investigate the changes of the expression of CPP32 and P53 protein following neuronal cell injury after focal cerebral ischemia in rats.
目的探讨大鼠脑缺血后神经元损害过程中CPP32和P5 3蛋白表达的变化。
Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser15 of human p53 protein.
该单克隆抗体是由合成的人源的针对p 53蛋白丝氨酸(15位)的磷酸化肽段免疫动物生产的。
P53 protein expression was studied with immunohistochemically in 15normal oral mucosas, 45 precancerous lesions and 21 invasive squamous cell carcinomas.
用免疫组化技术检测了15例正常口腔粘膜、45例癌前病变和21例浸润性鳞癌标本的P53蛋白的表达。
No correlation was found between the P53 protein overexpression and the clinical stages, neck lymph node metastasis, local recurrence and, survival of LSCC.
P 53蛋白表达与喉癌临床分期、分型、颈淋巴转移、局部复发及预后无相关性。
Objective to investigate the expression of MDM2 and P53 protein in osteosarcoma and its relation to the clinical-pathological parameters and prognosis of the tumor.
目的探讨骨肉瘤mdm2和P 53蛋白定位，表达水平，二者的相互关系及其对骨肉瘤转移及预后的影响。
They found that the p53 gene makes not only the well-established p53 protein, but also an alternative "control switch" variation of the p53 protein - known as an isoform.
他们发现p53基因不仅产生大家熟知的p53蛋白质，同时还产生一种p53蛋白质变换“控制开关”的变种——对碘氧基苯甲醚。
Methods:Immunohistochemistry and PCR-SSCP were used to detect the expression of P53 protein and p53 gene mutation in 32 cases of TSCC and 10 cases of tongue leukoplakia.
方法：应用免疫组织化学和聚合酶链反应—单链构象多态性分析（PCR-SSCP）检测10例舌白斑和32例舌癌，并结合临床资料进行分析。
Methods:Immunohistochemistry and PCR-SSCP were used to detect the expression of P53 protein and p53 gene mutation in 32 cases of TSCC and 10 cases of tongue leukoplakia.
方法：应用免疫组织化学和聚合酶链反应—单链构象多态性分析（PCR-SSCP）检测10例舌白斑和32例舌癌，并结合临床资料进行分析。
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