The second gene, p16, encodes a well known anti-cancer protein.
第二个基因是p 16，编码一种众所周知的抗癌蛋白。
Objective To study the expression of P16 protein in rectum cancer and the significance.
目的探讨P 16蛋白在直肠癌组织中的表达及其意义。
Aim: to study the expression of P16 in tissues of primary hepatocellular carcinoma (HCC).
目的；探讨原发性肝癌(HCC)中P 16蛋白的表达。
Conclusions The expression of VEGF, P53, and P16 was correlated with glioma malignant degree.
结论VEGF、P 53、P16在胶质瘤中的表达与其恶性程度相关。
Method: By S - P immunohistochemistry method, 60 cases were marked by P16 multiclonal antibody.
方法：应用P16多克隆抗体对60例肝癌用S-P法进行免疫组织化学标记。
Objective: to explore the risk factors of P16 protein abnormal expression in colorectal cancer (CRC).
目的：探讨大肠癌p 16基因异常表达的危险因素。
Purpose: To study the association of P16, VEGF and MVD with the biological behavior of human breast cancers.
目的：为研究多肿瘤抑制基因（p16）、血管内皮生长因子（VEGF）和肿瘤毛细血管密度（MVD）与乳腺癌生物学行为的关系。
Objective: To investigate the correlation of P16 protein expression in breast carcinoma with clinical stage.
目的：研究p 16蛋白在乳腺癌的表达及与临床分期的相关性。
The detection of P16, PCNA can evaluate the malignant degrees and may predict prognosis of ovarian carcinoma.
P 16和PCNA的检测可作为判断卵巢癌恶性程度和预测预后的参考指标。
The expression location of P16 protein could be a characteristic for identifying benign and malignant tissue.
P16蛋白的表达部位对良性及恶性病变可能具有鉴别意义；
CONCLUSIONS: positive and strongly positive expression of P16 in ca tissue implied risk of cancerization of ca.
结论：尖锐湿疣患者P 16蛋白阳性或强阳性表达提示有癌变的可能。
Objective To investigate the significance of P16 protein immunohistochemistry detection in in pediatric gliomas.
目的探讨P16蛋白免疫组织化学检测在小儿脑胶质瘤中的意义及其应用价值。
Conclusion the mutation of P16 gene may be related with the occurrence, tissue subtype and effectiveness in NHL.
结论P16基因缺失在NHL发病中起一定作用，其发生率与组织亚型和治疗效果有关。
To study the expression of PTEN, EGFR and P16 protein will build up target gene therapy foundation of astrocytoma.
通过对PTEN、EGFR、P 16蛋白的表达研究，为肿瘤的靶基因治疗策略提供了理论依据。
Results:In ALL, the incidence of P16 hypermethylation or homozygous deletion is 80%, there is no abnormal in control.
结果：AL LP16基因高度甲基化或纯合缺失发生率为80 % ，而对照组无一例P16基因失活；
Methods Immunohistochemical staining was used to determine the expression of P16 and P53 in 36 cases of retinoblastoma.
方法对36例视网膜母细胞瘤标本采用免疫组织化学方法观察P 16和P 53表达水平。
Results: The results showed that P16 expression was lower in thyroid adenomas than that in thyroid adenocarcinomas (p<0. 01).
结果：甲状腺癌P16蛋白表达量明显低于甲状腺腺瘤（P＜0。01）；
Objective:To study the expression of P16 protein and PCNA in ampullary carcinoma and its relation with its pathological features.
目的：探讨壶腹癌中抑癌基因P16蛋白与增殖细胞核抗原（PCNA）表达的相关性及其与肿瘤临床病理特征的关系。
Conclusion: the expression of P16 protein is related to the degree of the differentiation but not related to the size of the humors.
结论：提示P16蛋白的表达与肝细胞性肝癌的分化程度有关，与肿瘤大小有关。
Objective: To explore the alteration and the possible mechanism of tumor suppressor gene P16 in the progression of ovarian carcinoma.
目的：探讨卵巢癌病变中P16抑癌基因的改变和可能的作用机制。
The positive frequency of methylation of P16 gene promoter in HPP-CFC of normal contrasts was higher than that of psoriatic patients.
正常对照骨髓HPP-CFCP16基因启动子甲基化阳性率较高，而银屑病患者骨髓HPP-CFC P16基因启动子甲基化阳性率低于正常人。
The healthy cells saw their telomerase rise and p16 decrease, which would explain the boost in healthy cell growth, " Tollefsbol said."
健康细胞中端粒酶升高，而p16下降，这可以解释在健康细胞对生长过程的推动作用。
Objective To study the expression of P63 and P53, the relation between the expression of P63, P53 and PCNA, P16 in pancreatic neoplasms.
目的研究P53、P 63基因在胰腺肿瘤中的表达及其意义；P 63基因表达与P 53、增殖细胞核抗原(pcna)、P 16表达的关系及其意义。
Objective: to determine the expression of CDK4 and P16 and its relation to the clinicopathological characteristics in some epidermal tumors.
目的：探讨CDK4、P 16在某些表皮肿瘤中的表达及其与临床病理特征的关系。
Objective To observe the expression of cyclin kinase inhibitor P16 in pterygium and to investigate its effects on the pathogenesis of pterygium.
目的探讨翼状胬肉组织中细胞周期蛋白依赖性激酶抑制剂P16的表达，了解其在翼状胬肉发病机制中的作用。
Objective to investigate the relationship between the expression of P16 and P53 in brain astrocytoma with their grading of pathological histology.
目的探讨P 16和P 53蛋白的表达与脑星形细胞瘤的病理组织学分级的关系。
P16 is related to cell proliferation and apoptosis. Inducing apoptosis and inhabit cell proliferation can improve the clinical therapy effects of HCC.
P16的表达与细胞增殖和凋亡相关，通过导入野生型P 16诱导HCC中细胞凋亡或抑制其增殖，可望提高临床治疗效果。
When the proliferation signal was absent, high levels of p16 and COX-2 had the opposite effect: They allowed the cells to slow down and stop dividing.
当缺乏增殖信号时，高水平的p 16或COX - 2就表现出相反的作用，它们使细胞生长缓慢，停止分化。
When the proliferation signal was absent, high levels of p16 and COX-2 had the opposite effect: They allowed the cells to slow down and stop dividing.
当缺乏增殖信号时，高水平的p 16或COX - 2就表现出相反的作用，它们使细胞生长缓慢，停止分化。
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