Objective To solve the problem of non-inferiority test by adjusting central effect in multicenter trials.
目的解决校正中心效应的非劣性检验的问题。
Phase III studies are multicenter trials on large patient groups designed to be the definitive assessment of a drug's effectiveness.
三期研究是为最终评估药物有效性而在大批病人中进行的试验。
Benefit relative to placebo has been demonstrated in two large multicenter trials, with low doses (100 or 150 mg) having been shown to have therapeutic efficacy.
效益与使用安慰剂已经展示了两个大型的多中心临床试验(100或150毫克)低剂量后，被证明具有疗效。
The ACCP guidelines do not support the use of aspirin for prophylaxis following TJA, because this drug has not been extensively evaluated in multicenter randomized trials.
ACCP指南不支持在TJA术后使用阿斯匹林预防血栓性疾病，因为该药还没有在多中心随机试验中得到进一步评估。
There is clearly a need for prospective, multicenter, large-scale trials to aid surgical decision-making in the future regarding the treatment of distal humeral fractures.
对于肱骨远端骨折的治疗，尚需进一步实施大样本、多中心前瞻性研究以制定最佳的手术策略。
These patients had acne vulgaris ranging from mild to severe and were a subgroup of patients from phase 3, randomized, double-blind, vehicle-controlled, multicenter clinical trials.
这些患者有轻到重度痤疮，是基质对照随机双盲多中心3期临床试验的一个亚组。
However, larger, multicenter randomized trials comparing mechanical and chemoprophylaxis regimens are necessary to determine the true efficacy of these devices.
然而，还需做更大型的多中心随机试验来比较物理预防与药物预防的效果，从而确定这些物理预防方法真正的效果。
Further multicenter randomized clinical trials of larger sample size are needed to compare the effects of SLED and CVVH on the outcomes of postsurgical acute dialysis patients.
还需要进一步的多中心、随机、大样本临床实验来对比SLED和CVVH在术后紧急透析患者预后中的影响。
Further multicenter randomized clinical trials of larger sample size are needed to compare the effects of SLED and CVVH on the outcomes of postsurgical acute dialysis patients.
还需要进一步的多中心、随机、大样本临床实验来对比SLED和CVVH在术后紧急透析患者预后中的影响。
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