Objective To assessed the ability of FK506 and antilymphocyte serum(ALS) to induce mixed chimerism and tolerance for knee composite tissue allograft in rabbits without chronic immunosuppression.
目的探讨短期使用FK5 0 6和抗淋巴细胞血清（ALS）诱导兔同种异体膝关节移植嵌合耐受的作用。
Some experimental protocols were introduced including mixed chimerism of allogeneic bone marrow, blockade of co-stimulation signal and transgene technology for transplantation tolerance induction.
介绍一些具体方案，包括建立异基因骨髓嵌合体、阻断T细胞活化第二信号和转基因技术诱导移植免疫耐受。
Mixed hematopoietic chimerism is a state in which bone marrow hematopoietic stem cells from two genetically different individuals coexist.
造血干细胞混合嵌合体是指两个不同基因型个体的骨髓造血干细胞共存的一种状态。
Mixed hematopoietic chimerism is a state in which bone marrow hematopoietic stem cells from two genetically different individuals coexist.
造血干细胞混合嵌合体是指两个不同基因型个体的骨髓造血干细胞共存的一种状态。
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