Objective To discuss the relationship between estradiol and the mitogenic activated protein kinase signal transduction pathway and the expression of the MAPK in the MCF-7 breast cancer cell-line.
目的探讨雌二醇与有丝分裂素激活蛋白激酶（MAPK）信号通路的关系以及MAPK在乳腺癌细胞系中的表达情况。
Cyclin D1 which functions as a mitogenic sensor and allosteric activator of CDK4/6, is one of the more frequently altered cell cycle regulators in cancers.
细胞周期蛋白D1作为一个能促进有丝分裂和CDK4的变构激活剂，是癌症中较频繁变化的细胞周期调节子。
Cyclin D1 which functions as a mitogenic sensor and allosteric activator of CDK4/6, is one of the more frequently altered cell cycle regulators in cancers.
细胞周期蛋白D1作为一个能促进有丝分裂和CDK4的变构激活剂，是癌症中较频繁变化的细胞周期调节子。
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