Cyclin D1 which functions as a mitogenic sensor and allosteric activator of CDK4/6, is one of the more frequently altered cell cycle regulators in cancers.
细胞周期蛋白D1作为一个能促进有丝分裂和CDK4的变构激活剂，是癌症中较频繁变化的细胞周期调节子。
Concomitantly, this compound showed mitogenic activity when challenged with normal lymphocytes and was also found to be involved in the inflammatory response.
与此同时，表明这种化合物有丝分裂活动时，与正常细胞的挑战，同时也发现，参与炎症反应。
Objective To discuss the relationship between estradiol and the mitogenic activated protein kinase signal transduction pathway and the expression of the MAPK in the MCF-7 breast cancer cell-line.
目的探讨雌二醇与有丝分裂素激活蛋白激酶（MAPK）信号通路的关系以及MAPK在乳腺癌细胞系中的表达情况。
Objective To discuss the relationship between estradiol and the mitogenic activated protein kinase signal transduction pathway and the expression of the MAPK in the MCF-7 breast cancer cell-line.
目的探讨雌二醇与有丝分裂素激活蛋白激酶（MAPK）信号通路的关系以及MAPK在乳腺癌细胞系中的表达情况。
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