The TTW was extended in some degree when NGF combined with MK-801and Casepase-1 inhibitor by icv administration.
联合应用凋亡抑制剂能一定程度扩大有效治疗时间窗。
ICV administration allows not only lower systemic concentration but also higher therapeutically effective concentration within the CNS.
ICV给药不仅使全身浓度降低，还在CNS内获得了更高的治疗有效浓度。
Icv injection of IL 6 significantly stimulated gastric acid secretion by activating the vagal efferent system and the axis of HPA( P< 0 01).
中枢IL6可通过兴奋迷走神经释放乙酰胆碱，激活HPA轴产生皮质激素，促进胃酸的分泌（P< 0 0 1）。
Phentalamine and propranol ICV. injection can obviously block on vagus-pressor responses in 4~30 days old rabbits and obviously weaken vagus-pressor responses.
侧脑室注入酚妥拉明和心得安对4～30日龄兔的迷走-加压反应有明显的阻断作用，迷走-加压反应显著减弱。
METHODS the writhing model of mice induced by acetic acid, hot plate test (sc, icv), tail flick test and the model of electrical stimulation induced contraction of guinea pig ileum were used.
方法通过醋酸扭体模型、热板、甩尾、纳洛酮拮抗试验及豚鼠回肠离体标本研究样品的镇痛活性及机制。
METHODS the writhing model of mice induced by acetic acid, hot plate test (sc, icv), tail flick test and the model of electrical stimulation induced contraction of guinea pig ileum were used.
方法通过醋酸扭体模型、热板、甩尾、纳洛酮拮抗试验及豚鼠回肠离体标本研究样品的镇痛活性及机制。
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