ICV administration allows not only lower systemic concentration but also higher therapeutically effective concentration within the CNS.
ICV给药不仅使全身浓度降低,还在CNS内获得了更高的治疗有效浓度。
Phentalamine and propranol ICV. injection can obviously block on vagus-pressor responses in 4~30 days old rabbits and obviously weaken vagus-pressor responses.
侧脑室注入酚妥拉明和心得安对4~30日龄兔的迷走-加压反应有明显的阻断作用,迷走-加压反应显著减弱。
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