The TTW was extended in some degree when NGF combined with MK-801and Casepase-1 inhibitor by icv administration.
联合应用凋亡抑制剂能一定程度扩大有效治疗时间窗。
ICV administration allows not only lower systemic concentration but also higher therapeutically effective concentration within the CNS.
ICV给药不仅使全身浓度降低，还在CNS内获得了更高的治疗有效浓度。
Icv injection of IL 6 significantly stimulated gastric acid secretion by activating the vagal efferent system and the axis of HPA( P< 0 01).
中枢IL 6可通过兴奋迷走神经释放乙酰胆碱，激活HPA轴产生皮质激素，促进胃酸的分泌（P< 0 0 1）。
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