One of the biggest success stories of targeted therapy is a drug called Herceptin.
靶向治疗法最成功的故事之一是一种名为贺癌平的药物。
There were more serious side effects in the Herceptin group than in the observation group.
但赫赛汀治疗组严重副反应比观察组多。
The most dramatic success so far is Herceptin, a breast cancer treatment developed by Genentech.
这一领域至今为止最具戏剧性的成就是Herceptin——一种由Genentech开发的治疗乳腺癌的新药。
The researchers then looked at the drug Herceptin, which is used to treat HER2-positive breast cancer.
研究者们研究被用来治疗HER2阳性乳腺癌症的药物赫赛汀。
Herceptin is one such miracle drug that blocks a faulty gene pathway found in 30 percent of breast cancers.
贺癌平就是这样一种神奇的药物,它能堵住乳腺癌中发现的30%有瑕疵基因的路径。
In contrast, older drugs such as Herceptin have larger molecular structures that target the outside of the cell.
相反,象赫赛汀等药物作用靶点在细胞外,而且是大分子结构。
In 2007, Mexico guaranteed access to Herceptin for all women with breast cancer through a public insurance program.
2007年,墨西哥通过一项公共保险计划担保获得赫赛丁的生产授权,供所有患乳腺癌的妇女使用。
She started a tailored treatment plan that included eight months of chemotherapy using a combination of Taxol and Herceptin.
医生为她量身定做了一套治疗计划,其中包括了8个月的Taxol和赫塞汀混合化疗。
Nor did Herceptin have any effect on the HER2-negative cells, which is consistent with how Herceptin is used in the clinic.
赫赛汀对HER 2阴性的细胞也没有任何作用,即使在临床上赫赛汀的用量保持一致。
Perhaps the most famous of all targeted therapeutics is Genentech's (NYSE: DNA) Herceptin, which inhibits the HER2 receptor.
所有靶向治疗中最负盛名的可能就是基因泰克(Genentech)的Herceptin,该药可抑制HER2受体。
Herceptin is characteristic of a lot of these drugs: we only hear about the benefits and rarely about their downside or cost.
赫赛汀是许多这类药物的典型:我们只听到它们的治疗价值而很少听到它们的潜在危害或代价。
Further, the drug Herceptin, which is used to treat HER2-positive breast cancer, was found to target and destroy the cancer stem cells.
此外,发现用于治疗HER 2阳性乳腺癌的药物赫赛汀,能够靶向和摧毁癌症干细胞。
Objective To study the feasibility of adenoviral transduction of Herceptin complete antibody gene and its effect on Her2 over expressing cancer.
目的探讨应用基因治疗方法表达完全抗体的可行性及其对肿瘤的治疗作用。
These reports showed that even after short term follow up one year of Herceptin resulted in improved disease free, metastases free and overall survival.
这些报告表明,即使在短期内跟进一年赫赛汀导致改善无病,转移自由和整体存活率。
Unlike the hormonal treatment Herceptin, which is effective in only 20 per cent of patients with oestrogen-positive breast cancer, chemotherapy works for all women.
与赫赛汀激素疗法不同的是,赫赛汀激素疗法仅对20%雌激素阳性的乳腺癌患者有效,而该化疗是针对所有乳腺癌妇女的。
Hermillia Villegas, a 47-year-old mother of two in Jalisco, Mexico, recently learned that she had a virulent form of breast cancer that responded well to treatment with Herceptin.
赫尔米拉·比列加斯是位两个孩子的母亲,今年47岁,住在墨西哥哈利斯科州。她最近获悉自己得了一种恶性乳腺癌,目前使用赫赛丁效果很好。
The SPOT-Light test can measure how many HER2 genes are present in a sample of breast tumor; the more genes there are, the more likely the tumor will respond to treatment with Herceptin.
SPOT - Light检测可计算出一个乳腺癌样本中存在多少her 2基因;这种基因越多,用赫赛汀治疗肿瘤就越有效。
They found Herceptin reduced the number of cancer stem cells in the HER2-positive breast cancer cell lines by 80 percent, dropping it to the same levels seen in HER2-negative cell lines.
他们发现赫赛汀减少HER 2阳性乳腺癌症细胞系数量的80%,降至与her 2阴性细胞系相同的水平。
They found Herceptin reduced the number of cancer stem cells in the HER2-positive breast cancer cell lines by 80 percent, dropping it to the same levels seen in HER2-negative cell lines.
他们发现赫赛汀减少HER 2阳性乳腺癌症细胞系数量的80%,降至与her 2阴性细胞系相同的水平。
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