Its Herceptin also extended the life of women with certain types of breast cancer.
It appears to restore the effectiveness of Genentech 's Herceptin drug after that drug has failed.
Now Herceptin treatment is routine, and many women's lives are the better (and longer) for it.
Genentech's breast cancer drug Herceptin works only in women whose cancer has a particular mutated gene.
He said that pertuzumab in combination with Herceptin essentially provides a dual blockage of HER2.
Ninety-nine per cent said funding was provided for the MS drug, and 81% for Herceptin.
Herceptin targets a protein called HER2 found on tumors in about 20%-25% of breast-cancer patients.
But within six months of when she started Herceptin in 1992, Bradfield's tumors had all melted away.
Erbb2, or Her2, is the target of breast cancer drug Herceptin from Roche and lapatinib from GlaxoSmithkline.
He says mTOR may be a key resistance mechanism that cells use to evade the effects of Herceptin.
Twenty-five years ago he laid scientific groundwork for the breast cancer drug Herceptin, which is now a blockbuster.
Health authorities were asked about the provision of eight drugs approved by NICE, plus Beta interferon and Herceptin.
When considering a single medicine like Herceptin, the evaluation can be much quicker.
The row over Herceptin may be a foretaste of what is to come.
PCTs should not refuse to fund Herceptin solely on the grounds of cost.
Perjeta is a genetically engineered molecule that targets the HER-2 protein, the same protein targeted by the drug Herceptin.
FORBES: Exciting New Breast Cancer Drug Poised to Break the Bank?
Instead, it is designed to work in combination with Herceptin, each drug attacking the protein in a different way.
FORBES: Exciting New Breast Cancer Drug Poised to Break the Bank?
Herceptin was only the latest of a staggering three clinical successes the company has produced in the past month.
But Herceptin, too, was subject to scrutiny about its cost at the beginning.
Ongoing trials are testing Herceptin in combination with Tarceva in advanced breast cancer.
In early-stage breast cancer Herceptin doubles a woman's chances of living cancer free.
Herceptin then delivers the package to the tumor cell, where it releases the toxic cargo to kill the cancer.
Slamon was the force behind the first in a new generation of targeted cancer therapies: Herceptin, for advanced breast cancer.
This new data mean that some 200, 000 women may receive the genetic test to see if Herceptin might help them.
About one-third test positive for a protein called HER2 that makes cancers particularly aggressive, but susceptible to the drug Herceptin.
If so they can benefit from Herceptin, a drug which works on patients with high levels of the Her2 protein.
Zeneca's approach got a boost in late 1998 with the approval of Herceptin , a Genentech drug for advanced breast cancer.
The most famous example of this is the drug Herceptin, which is used in breast cancers with a certain genetic abnormality.
Herceptin is a breast cancer drug that was developed to treat tumors that have a specific mutation in the Her2 gene.
Despite Herceptin's success, the pharmaceutical industry seems loath to focus on developing other PM drugs, which often means reducing potential profits.
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