Adapalene was synthesized from 4-bromophenol by alkylation, etherification, condensation and hydrolysis with an overall yield of 51%.
对溴苯酚经烷基化、硫酸二甲酯醚化、缩合及水解反应制得阿达帕林，总收率51%。
Content of the products were quantitatively determined by two-phase chemical titration using bromophenol blue as the indicator and dichloroethane as the phase splitting agent.
以溴酚蓝为指示剂、二氯乙烷为分散相两相化学滴定法测定产物的含量。
The bromophenol compounds of the invention have inhibitory activity against protein tyrosine phosphatase (PTP1B), and can be used for treating the type 2 diabetes and the obesity.
本发明中的溴酚类化合物具有蛋白质酪氨酸磷酸酯酶(PTP1B)抑制活性，可用于治疗2型糖尿病和肥胖症。
The invention relates to a medicine for treating malignant tumor, in particular to an application of two bromophenol compounds to the preparation of the medicine for treating malignant tumor.
本发明涉及治疗恶性肿瘤的药物，具体地说是两种溴酚类化合物在制 备治疗恶性肿瘤药物中的应用。
The invention relates to a medicine for treating malignant tumor, in particular to an application of two bromophenol compounds to the preparation of the medicine for treating malignant tumor.
本发明涉及治疗恶性肿瘤的药物，具体地说是两种溴酚类化合物在制 备治疗恶性肿瘤药物中的应用。
应用推荐