It has become a very significant issue regarding how to accurately, comprehensively and quickly find the desired information within a narrow field of knowledge from the huge number of information.
如何快速、准确、全面地从浩瀚的信息资源中寻找到所要的狭小领域内的相关信息内容，已经成为了一项十分有意义的课题。
This is a very important issue, given the very significant public health implications of tobacco control for reduction of chronic diseases in future.
鉴于烟草控制对今后减少慢性病极为显著的公共卫生影响，这是一个很重要的问题。
"I'm sure some will take issue with their conclusions," he says, "but this is a very significant study."
他说：“我肯定有些人会反对她们的结论，但这是一项非常重要的研究。”
The fact that less than one percent of Facebook users have ever encountered a security issue on the site is a significant achievement of which we are very proud.
而实际上不到百分之一的Facebook用户曾在我们的网站上遭遇安全问题，这一事实是一项重大成就，更让我们非常自傲。
Trust model is the basis of trust mechanism. Due to the complexity of the trust itself, building efficient, high-precision trust model is still a challenging and very significant issue.
信任模型是信任机制的基础，由于信任本身的复杂性，构建高效、高精度的信任模型仍然是一个具有挑战性也非常有意义的课题。
How to explain the meaning of the text is a very complicated and significant issue.
如何阐释文本意义是个非常复杂又极其重要的问题。
Therefore, the comparative study on them is a very important and significant issue.
所以，对它们的比较研究便是一个非常重要和意义重大的课题。
Therefore, the comparative study on them is a very important and significant issue.
所以，对它们的比较研究便是一个非常重要和意义重大的课题。
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