同时还收集了3种鬼臼毒素类似物。
由此中间体可比较方便地合成鬼臼毒素。
This intermediates can be more convenient synthesis of podophyllotoxin.
目的寻找扩大获得鬼臼类物质资源的新途径。
Aim to search for a new method to produce more podophyllum substances.
应用硼氢化钠还原法合成三个硒代鬼臼毒素衍生物。
Three derivatives of selenoylpodophyllotoxin were composed with the reduce method. The synthetic process is temperate;
结论：该方法测定血清中鬼臼毒素简便易行，准确可靠。
Conclusion: The method is an easy, accurate and reliable way to determine podophyllotoxin in Serum.
测定脂质体鬼臼毒素壳聚糖膜剂中脂质体对鬼臼毒素的包封率。
To observe the podophyllotoxin liposome embedding ratio of liposome podophyllotoxin chitosan film.
目的探讨0 5 %脂质体鬼臼毒素壳聚糖膜剂制备的最佳配方。
Objective To explore the best formula of the 0 5% liposome podophyllotoxin chitosan film.
目的制备两种含有鬼臼毒素(PPT)的脂质体凝胶剂并比较两者的性能。
Objective to prepare two different liposome gels containing podophyllotoxin (PPT) and compare their pharmaceutical properties.
目的：鉴定日本正仓院中保存的我国唐代药物鬼臼的基原，考察鬼臼药用历史。
Objective: To identify the botanical origin of the Guijiu in Shosoin of Japan from Tang Dynasty, and trace its medicinal history.
用正交试验筛选鬼臼毒素冻干脂质体的优化工艺，并以HPLC法测定其包封率。
The orthogonal experimental design was used to optimize the preparation of podophyllotoxin freeze-dried liposomes. A HPLC method was used to determine the entrapment rate of the product.
制备鬼臼毒素脂质体混悬液并观察粒径、包封率、稳定性等指标，探讨其中的关系。
Prepare the podophyllotoxin liposomes liquid and observe its diameter, embedding ratio and stability, etc, and discuss the relation among them.
结果与结论：正仓院鬼臼来源于玉簪的地下部分，系我国唐代及其之前的鬼臼正品之一。
Result and Conclusion: Guijiu in Shosoin of Japan was derived from the underground parts of H. p…
结论：DPPC脂质体包裹鬼臼毒素外用具有更好的皮肤靶向性，是较好的皮肤外用制剂。
CONCLUSION: Podophyllotoxin liposome coated by DPPC is much more targetable to skin and is a fairly good topical preparation for applying on skin.
结果皮肤经微针预处理后进行鬼臼毒素透皮，其透皮速率是未经微针处理皮肤的5～11倍。
RESULTS The permeation rates of podophyllotoxin through the skin pretreated with microneedles are 5-11 times higher than that through the untreated one.
儿童低危型霍奇金氏病不必使用烷化剂、博莱霉素、鬼臼乙叉甙或大剂量扩野放疗等也可治愈。
Pediatric patients with low-risk Hodgkin's disease can be cured with therapy without an alkylating agent, bleomycin, etoposide, or high-dose, extended-field radiotherapy.
本试验对鬼臼多糖（PEP）进行提取和分离纯化、并通过实验研究探讨了鬼臼多糖的药理活性。
This paper is performed on extraction technology, purification and immune function of Podophyllum Emodi polysaccharides(PEP).
表鬼臼毒素2″，3″二脱氧糖苷的新型胺衍生物，其制备方法其作为药物的应用及其抗癌治疗的应用。
Amine derivatives of epipodophyllotoxin 2', 3'-dideoxyglycosides, preparation method therefor and use thereof as drug and for treating cancer.
方法：观察组大鼠涂抹脂质体鬼臼毒素混悬液(载药量0.5%)，对照组大鼠涂抹0.5%鬼臼毒素酊剂。
Methods 0.5% podophyllotoxin in liposome suspension or in alcohol solution (as control) were applied on the rat skin respectively.
目的研究鬼臼素衍生物cn - 2对人肺腺癌细胞A549的凋亡诱导作用，并对其分子机制进行初步探讨。
AIM: to study the apoptosis of human lung adenocarcinoma A549 cells induced by CN-2, a derivative of podophyllotoxin, and to obtain insights into its molecular mechanism of action.
鬼臼毒素sln具有较高的包封率，纳米粒粒径分布均匀，稳定性较好，可能制成一种有希望的皮肤外用制剂。
Podophyllotoxin SLN has high entrapment efficiency, an even distribution in size and a satisfactory stability, indicating that it might be a hopeful skin topical preparation in.
鬼臼毒素及其衍生物是一类具有显著生理活性的木脂素类化合物，其主要生理活性表现为抗肿瘤活性及抗病毒活性。
Podophyllotoxin as well as its derivatives exhibit a pronounced biological activity mainly as antitumor agents, which is a good source of the aryltetralin lignan.
通过上述研究，初步推测中肠肠壁细胞可能是鬼臼毒素的一个主要作用靶标，另外中肠蛋白酶也可能是其的作用靶标之一。
Based on above results, it can be concluded that one of the main action targets of podophyllotoxin was epithelial cells of the midgut, and the protease of midgut may also be one of its action targets.
通过上述研究，初步推测中肠肠壁细胞可能是鬼臼毒素的一个主要作用靶标，另外中肠蛋白酶也可能是其的作用靶标之一。
Based on above results, it can be concluded that one of the main action targets of podophyllotoxin was epithelial cells of the midgut, and the protease of midgut may also be one of its action targets.
应用推荐