阿片类药物造成的心理依赖作用提示与学习记忆功能有关。
Psychological dependence induced by opioids implicates the involvement of learning and memory function.
本文主要对内阿片肽在下丘脑中的分布特点及生理功能作了介绍。
In this review, the distribution and physiologic functions of endogenous opioid peptides in hypothalamus were discussed.
结果：阿片类戒断综合征中医辨证计量诊断指数表具有良好的诊断效能。
Results: the index form of the metric diagnosis and pattern differentiation of TCM against opium abstinent syndrome has favorable effective functions for the diagnosis.
目的研究阿片受体拮抗剂纳洛酮对大鼠脑震荡后空间学习记忆缺失的影响。
Objective to investigate the effects of naloxone a competitive opioid receptor antagonist on spatial learning and memory deficits following concussive brain injury in rats.
目的研究阿片受体拮抗剂纳洛酮对大鼠脑震荡后空间学习记忆缺失的影响。
Objective to investigate the effects of naloxone, a competitive opioid receptor antagonist, on spatial learning and memory deficits following concussive brain injury in rats.
本论文的工作显示了阿片类药物确实在海马的神经功能调控中起了重要作用。
The above work demonstrates that opiates play an important role in modulating the function of hippocampus.
以往的研究表明，内源性阿片肽（EOP）参与了EA对炎症痛镇痛的外周机制。
The previous studies suggested that endogenous opioid peptides (EOP) participate in the peripheral mechanism of electro-acupuncture (EA) analgesia for inflammatory-pain.
目的探讨脱毒后阿片类依赖者人格维度、特质层面的特点以及人格障碍的类型特征。
AIM: to explore the features of dimension and characteristics and to study the characteristics of the personality disorder types of opium addicts after detoxification.
近年来，椎管内应用阿片类药物因具有许多优点在临床麻醉和疼痛治疗中越来越受到重视。
In recent years, the intrathecal administration of opioids has been considered to be increasingly important in clinical anesthesia and pain management owing to its many advantages.
同时，精神科医生应该知道“高危人群应程序化选择用药，以减轻疼痛和将阿片类药物的使用最小化。”
Meanwhile, psychiatrists should be aware that “procedural options exist to relieve pain and minimize the use of opioids in this at-risk population, ” Panchal said.
提出了类阿片肽与丘脑下部—垂体—性腺轴相互作用的新见解以及需要进一步研究的理论问题。
The new concepts about the interactions between opioid peptides and hypothalamus-pituitary-gonadal axis and some theoretical problems further to be studied were suggested in this paper.
特别是有些药物能对阿片功能产生双向调节作用，即增强阿片镇痛，对抗阿片耐受和躯体依赖。
Especially, some of them show biphasic modulation on opioid functions, which enhance opioid analgesia, but inhibit tolerance to and substance dependence on opioids.
背景：隔-海马区的胆碱能神经通路是空间学习记忆的重要部位，此区神经元中又富含阿片受体。
BACKGROUND: the pathway of cholinergic nerve also with rich opium receptor in the septum-hippocampus areas is an important part for spatial learning memory.
阿片长期处理能够造成动物对阿片产生顽固性的病理性记忆，表明学习记忆参与了阿片依赖过程。
Refractory pathological memory on opioid will be generated in animals after chronic opioid treatment, which revealed the participation of learning and memory in opioid dependence.
内源及外源性阿片具有调节神经元与胶质细胞的功能，这些调节具有保护或损伤脑功能的双重作用。
Endogenous and exogenous opioids can influence and modulate neuronal and glial cell function via an opioid receptor mediated mechanism, leading to either protection or damage of the brain.
提示亮氨酸—脑啡肽可参与脑缺血的病理过程，血液稀释疗法也可能通过调节内源性阿片肽起作用。
The results suggest that leucine-enkephalin is probably involved in the pathophysiology of cerebral ischemia, and that hemodilution therapy may take effect by regulating endogenous opioid peptides.
纳洛酮为一特异性阿片受体阻滞剂，广泛用于麻醉剂过量、休克、酒精中毒、脑梗死等方面的治疗。
Naloxone is a narcotic antagonist that prevents or reverses the effects of opioids. It is widely used in the treatment of narcotics and alcohol intoxication, shock, cerebral infarct.
结论：蛛网膜下腔移植嗜铬细胞能有效缓解神经性疼痛，并能增强宿主对外源性阿片制剂的敏感性。
Conclusion: Transplanting xenogenetic chromaffin cells into subarachnoid space can reduce neuropathic pain effectively, and this antinociception is conducted via adrenoreceptors and opiate receptors.
然后研究者告知志愿者：给予（镇痛）药物注射（但实际上未作变化，志愿者继续接受同剂量阿片）。
The volunteers were then told that the drug would start being administered, although no change was actually made and they continued receiving the opioid at the same dose.
结论氯诺昔康用于痔疮切除手术术后镇痛是安全、有效的，能减少阿片类镇痛药的用量，副作用更少。
Intravenous Lornoxicam can effectively provide postoperative pain relief for after hemorrhoids operations with high effect and safeness, and reduce the dosage of Opium.
贝洛克说，这些结果很有趣，因为我们看到随着脑部阿片受体基因的改变，它控制着我们一顿饭吃多少。
"These results are interesting because we saw changes in opioid receptor gene expression in a brain area that controls how much we eat during a meal", said Bello.
受体亲和力决定了占据一定百分比的受体所需阿片类药物的量，而内在活性决定了阿片类药物的镇痛效果。
While receptor affinity determines the amount of opioid needed to occupy a given percentage of receptors, it is the intrinsic activity of the opioid that determines its analgesic efficacy.
痛力克是一种非甾体类抗炎药，曾被口服，肌注和静脉给药试图预防和减轻疼痛，减少对阿片类药物的需求。
Ketorolac, a nonsteroidal anti-inflammatory agent, has been administered orally, intramuscularly, and intravenously in an attempt to prevent and relieve pain and reduce opioid requirements.
脑啡肽是机体产生的一种类型的缓解疼痛感觉的阿片受体，但在慢性疼痛的情况下，这些物质似乎流量不够。
Enkephalins are a type of opiate that the body produces to dull pain sensations, but in cases of chronic pain, these agents appear not to flow in sufficient quantities.
目的探讨机体微循环在阿片类耐受、戒断过程中的不同变化，探讨温阳益气活血复方抗戒断症状的作用机理；
Objective The microcirculation changes in the process of opiate dependence abstinence and the mechanisms of anti - opiate dependence - abstinence syndromes of tradibional Chinese dugs were discussed.
因此识别那些有阿片参与控制成瘾环路的其他基因并设法绕过它们可能是治疗慢性疼痛的的更有效的另一种途径。
So identifying other genes — those that regulate the addiction circuits — and finding ways to bypass them could be another avenue to treating chronic pain more effectively with existing opiates.
异丁司特作为一种神经胶质激活和环核苷酸磷酸二酯酶抑制剂，已被显示有治疗神经性疼痛和阿片脱瘾的可能性。
Ibudilast, an inhibitor of glial activation and cyclic nucleotide phosphodiesterases, has shown potential in the treatment of neuropathic pain and opioid withdrawal.
根据美国疾病控制预中心所言，阿片类药物能强力缓解疼痛。但是他们会让人上瘾。过量服用这类药物可能会致命。
Opioids offer strong pain relief. But they are addictive, according to the Centers for Disease Control and Prevention. Taking too many or too much can be fatal.
结果：中医中药用于治疗阿片类物质依赖已有百余年的历史，积累了丰富和宝贵的经验，形成了一定的特色和优势。
RESULTS it is a century history for Chinese herbs to treat substance-dependence of opium so it has plentiful and precious experience and forms a certain of advantages.
比如那些富含类阿片与血清素的神经区域，在长期爱情中能够减轻焦虑与痛苦，产生一种镇定的感觉，在短期爱情中并没有出现。
For example, neural regions rich in opioids and serotonin, which relieve anxiety and pain and contribute to a sense of calm, did not light up for the newly-in-love.
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