然而，当我们再看深一点，问题开始出现了。
However, when we look a bit deeper, problems begin to emerge.
在问题开始出现之前，最近做了更改吗？
Did you implement any recent changes before the problem started appearing?
她认为那是问题开始出现的地方。
我个人的问题开始出现很长时间。
随着美元加速下滑，新问题开始出现。
这恰恰是问题开始出现的地方。
当需要集成时，问题开始出现。
When it comes time to integrate, that's where the problem begins.
金融危机爆发之后，各种问题开始出现。
然而，我们再看得深一点就发现，问题开始出现了。
However, when we look abit deeper, problems begin to emerge.
然而，由于心血管系统安全问题开始出现，受试者被迫停止服用塞来昔布。
However, subjects had to discontinue taking the drug as concerns about cardiovascular safety began to emerge.
这时，发生了以下情况：抱怨和问题开始出现。“我们为什么不能获得关于X的信息？”
Then it happens: The complaints and questions start to trickle in.
从另一种角度来看，这种转变更为重要，因为这使全新的一类(有可能)没有替代物的问题开始出现了。
In another sense the shift is more fundamental since it opens up a whole new class of (probably) non-equivalent problems.
当人类的活动破坏并加速的自然的温室气体量，人类产生了更多必需的量来维持地球理想温度的气体，问题开始出现了。
The problems begin when human activities distort and accelerate the natural process by creating more greenhouse gases in the atmosphere than are necessary to warm the planet to an ideal temperature.
从2003年起，这一问题开始出现。在1999年高校大幅度扩招以后，四年之后的2003年大学毕业生人数创历史新高。
The problem has been building since 2003, when a record number of students graduated four years after a dramatic expansion of further education in 1999.
问题于去年11月开始出现。
这位姓名不详的女子来自山东省，她从7、8岁开始出现咳嗽问题。
The unnamed woman from the province of Shandong started to have coughing problems when she was 7 or 8 years old.
苹果公司在这些问题上的立场是在斯诺登事件出现后形成的，在那之后，公司开始采用了一系列的技术，这些技术在默认情况下将使用者的数据加密，限制他人访问。
Apple's stance on these issues emerged post-Snowden, when the company started putting in place a series of technologies that, by default, make use of encryption to limit access to people's data.
当亚洲的一切似乎都出了问题时，就出现了疯狂推卸责任的现象；现在，当一些事情开始朝着好的方向发展时，就产生了一场争夺信誉的竞赛。
There was frantic blame-shifting when everything in Asia seemed to be going wrong; now there is a race to claim credit when some things have started to go right.
移居国外后，他们的关系开始出现问题了。
The relationship started to go wrong when they moved abroad.
肥胖、心脏病和糖尿病开始出现在以前从未出现过这些问题的人群中。
Obesity, heart disease and diabetes are beginning to appear in a people for whom these have never been problems before.
记忆力减退、做熟悉的任务出现困难、抽象思考出现问题，这些都是疾病开始的征兆。
Memory loss, difficulty in performing familiar tasks, and problems with abstract thinking are all indicators of the beginning of the disease.
更糟糕的是，当亚裔美国人确实开始出现在教科书上的时候，往往会伴随着一些问题。
Worse, when Asian Americans do make an appearance in lesson books, it is often laced with problems.
狩猎、设陷阱和制革等传统技艺开始消失时，身份危机问题随之出现。
There has been a crisis of identity as the traditional skills of hunting, trapping and preparing skins have begun to disappear.
随着时间的推移，他的房子开始出现一些问题。
我开始尝试时出现的最大的问题就是为什么这么做？
The big question that came up when I started the experiment was why?
但是，当到达50K用户时，我们开始观察到运行出现问题。
By 50 K users, however, we started to observe issues with the run.
开始在你的心里出现问题：用例是否会在这个项目中使用？
Questions begin spinning in your mind: Will use cases work on this project?
开始在你的心里出现问题：用例是否会在这个项目中使用？
Questions begin spinning in your mind: Will use cases work on this project?
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