为了应对DNA损伤,细胞有一套复杂的机制,包括细胞周期停滞,诱导转录和DNA修复被激活。
In response to DNA damage, the complex cellular mechanisms including cell cycle arrest, transcription induction and DNA repair are activated.
建立于目标基因激活和失活基础之上的几个化学分子诱导基因表达系统已有报道。
Various chemical inducible systems based on activation and inactivation of the target gene had been described.
牙周优势菌lps作用于单核巨噬细胞,诱导产生各种细胞因子和炎性介质,参与牙周病的炎症激活和组织创伤。
LPS involves in the inflammatory process and tissue destruction during periodontal diseases through inducing mononuclear macrophages to produce various cell factors and inflammatory mediators.
目的:cd3ak细胞是由抗cd3单克隆抗体和IL 2共同激活诱导的肿瘤杀伤细胞。
Objective: CD3AK cells were tumor-killing cells induced by costimulation of anti-CD3McAb and IL-2.
来自AT病人的细胞显示有缺陷的DNA损伤诱导检验点激活,对放射的敏感性和频率较高的染色体断裂(3,4)。
Cells from at patients display defective DNA damage-induced checkpoint activation, sensitivity to radiation, and a higher frequency of chromosome breakage (3, 4).
目的研究激活诱导细胞死亡(AICD)现象在乙型肝炎慢性化和重型化机制中的意义。
ObjectiveTo study the significance of AICD(activation-induced cell death) in the pathogenesis of chronic hepatitis B and chronic severe hepatitis B.
配基的结合诱导多聚化、自磷酸化和相应受体的激活[3 - 5]。
Ligand binding induces multimerization, autophosphorylation, and activation of these receptors (3-5).
配基的结合诱导多聚化、自磷酸化和相应受体的激活[3 - 5]。
Ligand binding induces multimerization, autophosphorylation, and activation of these receptors (3-5).
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