目的观察脑缺血再灌注损伤时血清和脑组织内洋地黄素水平变化和内洋地黄素拮抗剂地高辛抗血清对脑缺血再灌注损伤的干预作用。
AIM To evaluate the changes of serum and brain tissue endoxin in model of bilateral cerebral hemisphere ischemic reperfusion injury, and effect of anti digoxin antiserum (an antagonist of endoxin).
方法： 制备心肌组织缺氧模型，观察不同剂量的地高辛抗血清对缺氧损伤心肌组织内洋地黄素水平和心肌细胞膜ATP酶活性的影响。
METHODS: It was observed that different concentration of anti-digoxin antiserum effect on endoxin and cell membrane ATPase activity in hypoxic myocardium model.
结果： 模型组大鼠血清ROS水平明显升高，姜黄素可显著降低ROS水平（P＜0.05）；
RESULTS: Serum level of ROS in fibrotic group increased significantly compared with that of normal group, and which was depressed obviously in curcumin groups(P<0.05).
大黄素能与牛血清白蛋白非特异性结合形成复合物，引起吸收光谱红移55毫微米。
The absorption spectrum of emodin was changed by adding BSA. The shift of 55 nm in the absorption spectrum of emodin indicated the formation of a complex of emodin and BSA.
大黄素能与牛血清白蛋白非特异性结合形成复合物，引起吸收光谱红移55毫微米。
The absorption spectrum of emodin was changed by adding BSA. The shift of 55 nm in the absorption spectrum of emodin indicated the formation of a complex of emodin and BSA.
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