目的观察脑缺血再灌注损伤时血清和脑组织内洋地黄素水平变化和内洋地黄素拮抗剂地高辛抗血清对脑缺血再灌注损伤的干预作用。
AIM To evaluate the changes of serum and brain tissue endoxin in model of bilateral cerebral hemisphere ischemic reperfusion injury, and effect of anti digoxin antiserum (an antagonist of endoxin).
方法： 制备心肌组织缺氧模型，观察不同剂量的地高辛抗血清对缺氧损伤心肌组织内洋地黄素水平和心肌细胞膜ATP酶活性的影响。
METHODS: It was observed that different concentration of anti-digoxin antiserum effect on endoxin and cell membrane ATPase activity in hypoxic myocardium model.
结果： 模型组大鼠血清ROS水平明显升高，姜黄素可显著降低ROS水平（P＜0.05）；
RESULTS: Serum level of ROS in fibrotic group increased significantly compared with that of normal group, and which was depressed obviously in curcumin groups(P<0.05).
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