以较小量外源性胆固醇使肝游离胆固醇含量轻度升高，能明显抑制内源性胆固醇的合成。
When the free cholesterol content of the liver was slightly elevated by a small increase of dietary cholesterol, the rate of cholesterol synthesis decreased sharply in the liver of control animals.
当蛋白重组时，他汀类药物通过结合到一种特定的编码序列上来阻断LDL胆固醇的合成。
Statins block LDL cholesterol production by binding to a particular exon when the protein is assembled.
洋蓟抑制胆固醇的合成，从根本上降低总胆固醇、低密度脂蛋白胆固醇、甘油三脂的水平。
Third, inhibition of cholesterol synthesis artichoke, and fundamentally lower total cholesterol, low density lipoprotein cholesterol and triglyceride levels.
洋蓟抑制胆固醇的合成，从根本上降低总胆固醇、低密度脂蛋白胆固醇、甘油三脂的水平。
VI artichoke inhibition of cholesterol synthesis, a fundamental lower total cholesterol, LDL cholesterol, triglyceride levels.
在雌性中，通过从胆固醇中合成雄烯二酮，开始在卵巢的间膜细胞中合成雌激素。
In females, synthesis of estrogens starts in theca interna cells in the ovary, by the synthesis of androstenedione from cholesterol.
你知道你的身体需要胆固醇来利用阳光合成维生素d吗？
Did you know that your body needs cholesterol to synthesize sunlight into vitamin d?
人体需要胆固醇和甘油三酯来合成细胞膜，但过多或过少都会引起用严重的健康问题。
The body needs cholesterol and triglycerides for energy and to build cell membranes, but too much or too little can cause serious health problems.
合成代谢类固醇的潜在副作用包括高血压，胆固醇值变动，情绪无常，粉刺，还有过早秃头。
Anabolic steroids' potential side-effects include elevated blood pressure, changes to cholesterol levels, mood swings, acne and premature balding.
综述了胆固醇生物合成过程及生物合成过程中关键酶抑制剂的研究开发现状。
Cholesterol biosynthetic pathway, status of research and development on inhibitors of key enzymes in cholesterol biosynthesis were reviewed.
胆固醇是由人体自然合成的脂肪物质，很多食物中也含有胆固醇。
Cholesterol is a fatty substance made naturally by the body and also found in many foods.
结论：化合物sipi -1 -3和4为首次报道的新结构化合物，抑制胆固醇生物合成活性也为新发现。
CONLUSION: Compound SIPI 1 3 and 4 were first reported with new structures, Their lowering cholesterol biosynthesis activities were first found so far.
酰基辅酶A：胆固醇酰基转移酶（ACAT）是细胞内唯一合成胆固醇酯的酶，在细胞和生物体胆固醇代谢平衡中起非常重要的作用。
Acyl-CoA: cholesterol acyltransferase(ACAT) is an intracellular enzyme that catalyzes the formation of cholesterol esters from long-chain fatty acyl coenzyme A and cholesterol.
首次合成出水溶性两亲性含胆固醇基的羧甲基纤维素钠衍生物(CCSD)。
The water soluble amphiphilic cholesteryl-bearing carboxymethylcellulose sodium derivative (CCSD) was first synthesized with the help of coupling agent and catalyst at room temperature.
从自然界含量丰富的胆固醇和简单芳香衍生物出发，经过简单的合成即可得到凝胶的前体。
Cholesterol abundant in the nature and simple aromatic derivative can be made into gel precursor just through simple synthesis.
在昆虫中，胆固醇不仅是细胞膜的重要成分之一，也是昆虫蜕皮激素生物合成的前体。
In insects, cholesterol is not only one of the main components of cell membranes, but also a precursor of ecdysone biosynthesis.
美伐他汀是3羟甲基戊二酰辅酶a还原酶的有效的竞争性抑制剂，它是一种胆固醇生物合成调解酶。
Mevastatin is a potent competitive inhibitor of 3-hydroxy-3-methyl-glutaryl-coa reductase, a regulatory enzyme for cholesterol biosynthesis.
美伐他汀是3羟甲基戊二酰辅酶a还原酶的有效的竞争性抑制剂，它是一种胆固醇生物合成调解酶。
Mevastatin is a potent competitive inhibitor of 3-hydroxy-3-methyl-glutaryl (HMG) -coa reductase, a regulatory enzyme for cholesterol biosynthesis.
美伐他汀是3羟甲基戊二酰辅酶a还原酶的有效的竞争性抑制剂，它是一种胆固醇生物合成调解酶。
Mevastatin is a potent competitive inhibitor of 3-hydroxy-3-methyl-glutaryl (HMG) -coa reductase, a regulatory enzyme for cholesterol biosynthesis.
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