人类基因组计划(HumanGenomeProject)的目标之一就是要让研究者找出单个基因多个变体(亦即等位基因)与特定疾病之间的关联。
One of the goals of the Human Genome Project was to allow researchers to link versions of individual genes (known as alleles) with particular diseases.
其中HLA-DQA1等位基因的分布及其与疾病关联受到很大的关注。
Moreover, HLA-DQA1 allelic distribution and association with diseases should be paid great attention.
PV患者血清瘦素水平显著增高，并与HLA等位基因相关联，提示HLA等位基因和瘦素参与PV发病过程。
These results together suggest that HLA alleles are involved in modulating serum leptin levels and might be predisposition alleles for PV in the studied population.
目的探索内蒙地区蒙古族儿童过敏性紫癜及其累及肾脏、胃肠道和关节与HLA -DRB1等位基因的关联性。
Objective to explore the correlation between HLA-DRB1 allele and anaphylactoid purpura and its association with kidney, gastrointestinal and joint in juvenile of Mongolian residing in Inner Mongolia.
目的研究中国人群中载脂蛋白E等位基因型与阿尔茨海默病的关联。
Objective To analyse the association of apolipoprotein E genotypes with Alzheimer' s disease in Chinese population.
按照吸烟特点进行亚组分析：在等位基因比较、纯合子比较、隐性遗传模型和显性遗传模型下，都没有发现吸烟与肺癌有显著关联。
In the subgroup analysis stratified by smoking status, no association of smoking was found between 12139c allele and lung cancer under different genetic models.
按照吸烟特点进行亚组分析：在等位基因比较、纯合子比较、隐性遗传模型和显性遗传模型下，都没有发现吸烟与肺癌有显著关联。
In the subgroup analysis stratified by smoking status, no association of smoking was found between 12139c allele and lung cancer under different genetic models.
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