稳态血药浓度峰值和谷值与体重剂量呈正相关;
There is positive correlation between peak and trough steady-state concentration and the body weight doses.
目的研究氯氮平不同剂量时稳态血药浓度与临床效应的关系。
Objective the study investigated the relationship between serum level and clinical response to clozapine in different dose for treating schizophrenic patients.
结果:稳态血药浓度与给药剂量、给药时间、是否联合用药等有着密切的关系。
Results: There is a close relation between the drug serum concentration in stable state and the administration dosage, interval and weather associated with other epileptic drugs.
所有患者万古霉素治疗5天或以上的,应至少有1稳态血药浓度槽前第四剂量测量。
All patients treated with vancomycin for 5 days or more should have at least 1 steady-state trough serum concentration measured just before the fourth dose.
疗效和不良反应分别用简明精神病评定量表(BPRS)和副反应量表(TESS)进行评定,并测定治疗第1,2,4,6周的稳态血药浓度。
Therapeutic efficacy was measured by BPRS and the adverse reaction was rated by TESS. Steady serum level was monitored within 1, 2, 4, 6 week.
疗效和不良反应分别用简明精神病评定量表(BPRS)和副反应量表(TESS)进行评定,并测定治疗第1,2,4,6周的稳态血药浓度。
Therapeutic efficacy was measured by BPRS and the adverse reaction was rated by TESS. Steady serum level was monitored within 1, 2, 4, 6 week.
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