细胞骨架微管和肌动蛋白都参与了细胞核定位的过程。
Both microtubule and actin cytoskeleton have been shown to be involved in proper nuclear positioning.
因为存在一个推测的核定位基序,这个蛋白可能在细胞核中起作用。
Because this protein has a putative nuclear localization motif, it probably functions in the nucleus.
核定位序列(NLS)是信号蛋白分子上与入核转运相关的氨基酸序列。
Nuclear localization sequence(NLS) is the specific amino acid sequence on the signaling proteins to be sufficient for their nuclear translocation.
他们的技术自动追踪每个细胞的核定位,并将其外观分为16种不同类型。
Their technique automatically tracked the position of the nucleus in each cell and classified its appearance into 16 different categories.
免疫组织化学方法检测石蜡包埋的人乳腺癌组织,图示为核定位。使用的抗体为53bp1。
Immunohistochemical analysis of paraffin-embedded human breast carcinoma, showing nuclear localization, using 53bp1 Antibody.
结论PTEN过度表达将引起肾脏成纤维细胞周期G 1期阻滞,这一过程与PTEN在细胞核定位有关。
Conclusion Overexpression of PTEN will induce G1 arrest in rar renal fibroblast cells, which associated with the nuclear location of PTEN.
本研究旨在对BRD7的核定位信号进行预测、结构分析和功能鉴定,并考察其对BRD7亚细胞定位的影响。
Objective: To structurally analyse and functionally identify the nuclear localization signal (NLS) in BRD7 and then study its effect on the subcellular localization of BRD7.
目的寻找与人巨细胞病毒(HCMV)PPUL44蛋白核定位信号(NLS)具有较强结合能力的多肽,研究这些多肽的氨基酸序列特点。
Objective To find the peptides that have strong binding ability to the nuclear localization signals (NLS) of human Cytomegalovirus (HCMV) PPUL44 protein, and to analyze their amino acid sequences.
结论:BRD7的65 ~ 96位氨基酸残基为BRD7功能性核定位信号所在区域,在BRD7胞核分布模式中发挥了十分重要的作用。
Conclusion: The amino acid region from 65 to 96 is a functional NLS in BRD7 and it is an essential motif affecting BRD7 nuclear distribution.
结论:BRD7的65 ~ 96位氨基酸残基为BRD7功能性核定位信号所在区域,在BRD7胞核分布模式中发挥了十分重要的作用。
Conclusion: The amino acid region from 65 to 96 is a functional NLS in BRD7 and it is an essential motif affecting BRD7 nuclear distribution.
应用推荐