• 细胞骨架微管和肌动蛋白都参与了细胞核定位的过程。

    Both microtubule and actin cytoskeleton have been shown to be involved in proper nuclear positioning.

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  • 因为存在一个推测的核定位基序,这个蛋白可能在细胞核中起作用。

    Because this protein has a putative nuclear localization motif, it probably functions in the nucleus.

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  • 核定位序列(NLS)是信号蛋白分子上与入核转运相关的氨基酸序列。

    Nuclear localization sequence(NLS) is the specific amino acid sequence on the signaling proteins to be sufficient for their nuclear translocation.

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  • 他们的技术自动追踪每个细胞的核定位,并将其外观分为16种不同类型。

    Their technique automatically tracked the position of the nucleus in each cell and classified its appearance into 16 different categories.

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  • 免疫组织化学方法检测石蜡包埋的人乳腺癌组织,图示为核定位。使用的抗体为53bp1。

    Immunohistochemical analysis of paraffin-embedded human breast carcinoma, showing nuclear localization, using 53bp1 Antibody.

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  • 结论PTEN过度表达将引起肾脏成纤维细胞周期G 1期阻滞,这一过程与PTEN在细胞核定位有关。

    Conclusion Overexpression of PTEN will induce G1 arrest in rar renal fibroblast cells, which associated with the nuclear location of PTEN.

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  • 本研究旨在对BRD7的核定位信号进行预测、结构分析和功能鉴定,并考察其对BRD7亚细胞定位的影响。

    Objective: To structurally analyse and functionally identify the nuclear localization signal (NLS) in BRD7 and then study its effect on the subcellular localization of BRD7.

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  • 目的寻找与人巨细胞病毒(HCMV)PPUL44蛋白核定位信号(NLS)具有较强结合能力的多肽,研究这些多肽的氨基酸序列特点。

    Objective To find the peptides that have strong binding ability to the nuclear localization signals (NLS) of human Cytomegalovirus (HCMV) PPUL44 protein, and to analyze their amino acid sequences.

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  • 结论:BRD7的65 ~ 96位氨基酸残基为BRD7功能性核定位信号所在区域,在BRD7胞核分布模式中发挥了十分重要的作用。

    Conclusion: The amino acid region from 65 to 96 is a functional NLS in BRD7 and it is an essential motif affecting BRD7 nuclear distribution.

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  • 结论:BRD7的65 ~ 96位氨基酸残基为BRD7功能性核定位信号所在区域,在BRD7胞核分布模式中发挥了十分重要的作用。

    Conclusion: The amino acid region from 65 to 96 is a functional NLS in BRD7 and it is an essential motif affecting BRD7 nuclear distribution.

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