研究人类中由于基因缺失或基因不表达而引发的疾病。
Diseases that are the result of loss of expression or missing genes in humans will also be studied.
在来自相同病人的正常肺组织中没有发现基因缺失或突变。
No missing genes or mutations were observed in normal lung tissues from the same patients.
结论GSTM 1基因缺失与老年性白内障的发生缺乏显著关系。
Conclusion GSTM1 gene deletion is not related to senile cataract formation.
目的：建立对男性无精症病人YRRM1的基因缺失诊断方法。
Objective: In order to establish a method to detect the abnormal YRRM1 gene in azoospermia.
如果SRY基因缺失，即使胚胎是男性的，其性腺也会发育成卵巢。
If SRY is missing, the gonad develops into an ovary, even if the embryo is male.
它也能够用于测试各种各样svz神经干细胞基因缺失所产生的影响。
It can also be used to test the impact of deleting various genes from neural stem cells of the SVZ.
结论GMCSF基因缺失影响创面的新生血管化能力，进而影响创面的愈合。
Conclusions GMCSF-absence inhibits neovascularization during wound repair and leads to the delay of wound healing.
波士顿儿童医院的研究人员发现，每一百万个基因缺失就会使身高下降八分之一英寸。 。
Thee researchers from the Children's Hospital Boston found that for every million individual deletions, one eighth of an inch in height was lost in people.
结论P16基因缺失在NHL发病中起一定作用，其发生率与组织亚型和治疗效果有关。
Conclusion the mutation of P16 gene may be related with the occurrence, tissue subtype and effectiveness in NHL.
结论：atm基因缺失可能与卵巢癌的发生机制有关，有可能成为卵巢癌治疗新的分子靶点。
CONCLUSIONS: the deletion of ATM gene may play a role in the development of ovarian cancer. ATM gene may be identified as a potential target in gene therapy.
而且，红藻氨酸盐诱导的Gamma节律信号可以被RAGE基因缺失或抗体阻断的方式减弱。
Moreover, the kainate-induced gamma oscillations were attenuated by the genetic deletion or antibody blockade of RAGE in vivo.
目的探讨血管紧张素转化酶(ace)基因缺失多态性与中国人脑梗死、高血压性脑出血的关系。
Objective To investigate the relationship between the angiotensin converting enzyme (ACE) gene deletion polymorphism and cerebral infarction, hypertensive cerebral hemorrhage in Chinese.
他们观察到，不仅在变异总量上，而且在具体的基因缺失上，精神分裂症患者的数目变异明显超过了躁郁症患者。
They observed a significant excess of variations in those with schizophrenia compared with those who had bipolar disorder both for total number of variations and for gene deletions specifically.
本发明还公开了所述基因缺失菌株在制备支气管败血波氏杆菌基因缺失疫苗（弱毒活疫苗）的应用。
The invention also discloses the application of the gene deleted bacterial strain in preparing the Bordetella bronchiseptica gene deleted vaccine (attenuated live vaccine).
为了发现肾上腺钟是如何控制的，研究者在不同的时间处理了小鼠和时钟基因缺失的小鼠的肾上腺切片。
To find out how the adrenal clock ticks, the researchers first treated slices of adrenal tissue from normal mice and mice lacking critical clock genes at different time points.
结论电生理检查对HNPP的诊断很重要，基因检测发现PMP22基因缺失是诊断HNPP的金标准。
The PMP22 gene deletion detected by gene diagnosis is the golden criterion for the diagnosis of HNPP.
该基因缺失会导致动物骨骼肌肌纤维数量增多或肌细胞肥大等现象，这对肉用养鹿业有潜在的应用价值。
The deficiency of this gene would cause the increasing of the quantity animal skeleton muscles fiber and becoming fleshy of muscle cells, there is latent using value on flesh deer.
结论在染色体异常核型中，均有不同程度的基因缺失，造成基因连锁的不平衡，因而出现一些临床效应。
Conclusion: gene have different degree loses in abnormal chromosome karyogram, result in chromosomal gene linkage not equilibrium and and emergence clinical effect.
目的：检测脆性组氨酸三联体基因在胃癌组织中等位基因缺失和突变情况，分析该异常在胃癌发生中的作用。
Objective: to detect allelic deletion and mutation of FHIT gene in gastric cancer, and to analyze the role of the abnormalities in the carcinogenesis of gastric cancer.
他们目前计划研究这些丢失基因的作用。早期的研究表明这些基因缺失可能与发育迟缓，自闭症和精神分裂症有关联。
They now plan to study the function of the missing genes. Previous studies have suggested that deletions of these genes may be linked with delayed development, autism and schizophrenia.
结论GSTM1基因缺陷型可能是非吸烟女性患肺癌的重要危险因素，GSTT1基因缺失则可能与肺癌的发生无关。
Conclusion GSTM1 deletion may be an important host risk for lung cancer in nonsmoking women, whereas GSTT1 deletion is not associated with the risk to lung cancer in women.
正在应用的或处于研究阶段的构建瘤胃基因工程菌的方式主要有基因缺失技术、基因复制性重组技术和启动子的应用技术。
The main methods used, or under investigation, for production of rumen gene engineering bacteria are:gene deletion technique, gene recombination technique and the application of promotor.
PTEN基因缺失的CARN细胞的小鼠很快就产生肿瘤，同时，有功能的PTEN基因的CARN细胞的小鼠则不产生肿瘤。
Mice with CARN cells lacking PTEN quickly developed carcinomas, whereas mice with functional PTEN in CARN cells did not.
结论3例FA-A型患者均无功能性FANCA蛋白表达；基因缺失、移码突变和剪切位点突变是FANCA基因的主要失活方式。
Conclusions No functional FANCA protein was found in these 3 cases of FA-A, and intragenic deletion, frame shift and splice site mutation were the major pathogenic mutations found in FANCA gene.
尽管如此，这仍是我们第一次从跨越多个人群的大容量样本中鉴别出于精神分裂症有关的基因缺失，stefansson补充道。
Nevertheless, these are the first deletions associated with schizophrenia to be identified in such a large sample and across several populations, stefansson adds.
这项研究是“描述基因缺失如何与大脑机能障碍相关的重要步骤，”她接着说，“无论有没有基因被证明是精神分裂症的普遍病因，这都是重要的信息。”
This is important information whether or not any of [the genes involved] turn out to be common causes of schizophrenia in the population.
这项研究是“描述基因缺失如何与大脑机能障碍相关的重要步骤，”她接着说，“无论有没有基因被证明是精神分裂症的普遍病因，这都是重要的信息。”
This is important information whether or not any of [the genes involved] turn out to be common causes of schizophrenia in the population.
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