p16蛋白及其基因在原发性肝细胞癌中的表达缺失_医学杂志_健康小常识K210.com Keywords】 carcinoma, hepatocellular; gene deletion; p16 protein [gap=373]关键词】 肝细胞癌; 基因缺失; p16蛋白
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一、基因突变的形式 点突变(point mutation)基因缺失(gene losses)基因异位或重排 (gene translocation and rearrangment)
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基因缺失活疫苗 gene deleted live vaccine
基因缺失疫苗 gene-deleted vaccine ; Gene deletion vaccines
基因缺失鼠 gene knockout mice
分部等位基因缺失 FAL
猪伪狂犬基因缺失活苗 AKIPOR
染色体基因缺失 losses of chromosome
基因缺失突变株 gene deleted mutant
结直肠癌缺失基因抗体 Anti-DCC
基因杂合性缺失 Loss of Heterozygosity ; LOH
When the gene deletion、mutation、and promoter CPG island aberrant methylation of p16 protein make p16 abnormal expression, it would lead the growing cell lost of control, cell transmission and carcinoalteration.
当P16蛋白基因缺失、突变、启动子CPG岛异常甲基化使其表达异常时,同样导致细胞生长失控、细胞转化和癌变。
参考来源 - 早中期食管鳞状细胞癌中P16、PCNA表达研究·2,447,543篇论文数据,部分数据来源于NoteExpress
在来自相同病人的正常肺组织中没有发现基因缺失或突变。
No missing genes or mutations were observed in normal lung tissues from the same patients.
如果SRY基因缺失,即使胚胎是男性的,其性腺也会发育成卵巢。
If SRY is missing, the gonad develops into an ovary, even if the embryo is male.
波士顿儿童医院的研究人员发现,每一百万个基因缺失就会使身高下降八分之一英寸。 。
Thee researchers from the Children's Hospital Boston found that for every million individual deletions, one eighth of an inch in height was lost in people.
You get the idea here, is to deliver the gene that you're interested in directly to the tissue where it's being used and in this case, the idea is to introduce a gene that's missing.
但首先你要明确,这种思路是用来将,某个目的基因直接导入,它原本就能被利用的组织中的,此例中是导入一种缺失的基因
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