The surprise drop in sales compared with last year threw a wrench into the company's fiscal expectations, CEO William L.McCombWilliam L. McComb said.

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Instead, in his prepared remarks, Kindler seems to be emphasizing the drugmaker's ability to wrench big efficiencies out of its enormous structure--a strategy not that different from the cost-cutting going on at rival Merck.

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There's a big monkey wrench in the machinery this year, however.

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Some critics said the industry's move could throw a wrench in a separate year-long effort by the World Wide Web consortium to set an international standard for do-not-track.

WSJ: Web Companies Agree to Support 'Do Not Track' System

Before his promotion, two things explained Mr Mandelson's low standing: a reputation as a schemer, and his work during Labour's bleak years of opposition to wrench the party to the right.

ECONOMIST: The white heat of Mandelson

The Surface's built-in kickstand threw another wrench into the design process, as did the magnetic hinge used to attach the keyboard covers.

ENGADGET: Microsoft Surface: inside the three-year secret project to build the first great Windows tablet

When you - you're crack climbing a thin crack, you stick your toes into the crack and then kind of wrench down on to stand up, and it's painful.

NPR: Craig DeMartino: Winner in the Extremity Games

Real estate brokerage Realogy sought to skirt defaults on some of its bonds by launching a debt exchange but CarlIcahn'Carl Icahn's venture-capital firm, High River , threw a wrench in its plans by slapping Realogy with a lawsuit and accusing it of delaying the inevitable.

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