Top Wall Street bankers are scrambling for a solution to their biggest headache these days: Lehman Brothers .
With iPhone, Steve Jobs and Apple pulled off their biggest and most comprehensive market systems coup.
This will be a great relief to their shareholders, especially their biggest shareholder, the Treasury.
In August remittances from Mexicans working north of the border suffered their biggest drop on record.
For brands, they can log in and see who their biggest customers are, then reward them.
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Drug firms have had trouble inventing new medicines, but their biggest problem may be testing them.
Visa and Mastercard recorded their biggest intraday stock declines in years when the news was released.
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The companies feel like they have solved their biggest problems, related to union contracts and debt.
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One of their biggest challenges is that they can't drive up to the castle.
"Their biggest problem was that they needed a new stadium, " says Denver Broncos owner Patrick Bowlen.
The Red Bulls have also had their title hopes dashed quite often by their biggest rival.
Some 11% of those surveyed said that pay was their biggest source of stress.
Of course, she eventually did get in to VS and became one of their biggest models.
Apple's retail stores had their biggest sales day of all time, according to published reports.
Not long after joining UBS his team solicited from advisors a list of their biggest complaints.
American troops would rub shoulders less often with their biggest NATO allies, especially Germany.
But first, New Hampshire primary voters, this week, reiterated their biggest concern is the economy.
Shares in Samsung fell 7% in Seoul trading, their biggest one-day fall in almost four years.
At their biggest-ever conference last weekend, most participants' conversations began with questions about coming out.
In 2001 the two septuagenarians pulled off what might turn out to be their biggest coup.
For nearly a decade the government was their owner, and their biggest customer for loans.
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Summer is a crucial season for Hollywood, when the studios roll our their biggest, most expensive films.
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And, considering that for most companies the marketing budget is their biggest expense, this is a head-scratcher.
That facility is used only a few times a year by the members, during their biggest events.
As the decade progressed, Tribune's management kept asking their biggest customers, their newspaper advertisers, what to do.
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It's right that nurses and midwives this year got their biggest national pay rise for a decade.
Three years ago, Japan was their biggest market in terms of square footage and net asset values.
One of their biggest hits was "Boogie Woogie Bugle Boy, " which became a World War II anthem.
These happen to be the areas where Central and Eastern European countries have their biggest comparative advantage.
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And the Ospreys seven tries to two rout was their biggest triumph for more than two years.
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