And sometimes its hard that first time through to use all your pitches.
Matt Herper: Speeding forward a decade: Why did you decide to file for approval, FDA approval, that first time, given that the studies had missed their primary endpoints and that a third study, the IMPACT trial, was already going on?
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That marks the first time that either first or second quarter spending has dropped with respect to the previous quarter since 2003.
The two games that the teams will play against each other will mark the sixth edition of the event, which when launched in 2004, marked the first time that an American professional sports league played games in China. 2012 will be the first time that an NBA championship winning team has competed in the China Games.
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Genomic knowledge, of humans and other species, will transform medicine by introducing side-effect-free drugs that work first time, expanding the range of diseases that are treatable and refining diagnosis.
We believe that is the first time that the welcome factor has been measured in a quantitative way beyond self-reporting.
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That was the first time that I had seen a Carrera or a Monaco and those designs just clicked and hooked me into the vintage Heuer world.
"As we're sitting around talking about our rashes, that was the first time that I actually felt like other people understood what I had gone through, " she said.
The Guangzhou-based developer added that first-time home buyers made up 64% of its sales last month, and that most of its sales were in second- and third-tier cities.
As far as your general point's concerned about the threat of legal action, I have to tell you that it's not the first time that secretaries of state in Northern Ireland have had legal actions taken against them, nor even the first time by Dr Paisley.
BBC: News | BREAKFAST WITH FROST | Dr John Reid MP, Secretary for Northern Ireland
However Mr Fowlis warned that first-time buyer numbers still represented only 46% of the figure before the 2008 economic crisis.
BBC: First-time buyers help boost monthly house sales by 21%
He noted that the first time he ran for Congress, he started down by 20 points and won by 8 percent.
The Labor Department reported that first-time filings for jobless benefits fell by 21, 000 to 454, 000, below the 465, 000 Wall Street had anticipated.
Research by the Bank of England also showed that first-time buyers face having to find bigger deposits when getting on the property ladder.
In notable economic news this week, the Labor Department announced that first-time jobless benefits claims fell by 5, 000 to 366, 000 this past week.
And also celebrating that for the first time in years that some of the youth in this country were starting to think for themselves.
But he noted that for the first time this year that when compiling data for supply and demand tables, his firm is adding a new category: diamond recycling.
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Head bartender Jan Warren admits that first-time guests are sometimes "a little freaked out" by Dutch Kills' location on a deserted industrial street with a spooky lit-up "BAR" sign.
Sicignano testified that the first time he knew such arrangements were made was when former New York Knick John Starks -- one of Kaplan's favorite sports figures -- visited the club.
Veteran Ernie Els broke that first-time trend at Royal Lytham last month when he denied Adam Scott his maiden major -- the South African claimed his first since 2002 and fourth overall.
So I think that this is the first time that I've really married my sort of sense of being barraged by consumer messages with my choice and who I'm going to vote for.
The Sun Inn is the sort of traditional boozer that first-time visitors to England may have imagined only existed in films, with the added attraction of plentiful fresh seafood, like scampi and chips on offer.
"It's a bonding experience, one that very few people in the world have ever had, " said trainer Dean O'Malley, adding that first-time users typically managed to reach heights of 10 to 15 feet with the jet pack.
But given the regular appearances and the schools' 17 combined Sweet 16 appearances since 1985, you might be surprised to learn that 2013 is the first time that both Michigan and Michigan State have made the tourney's regional semifinals in the same year.
And I read a report today that the first time it was mentioned - or there was a tiny little mention about it in a Huffington Post story, and it was the exact same day, if not week, that the Sandra Fluke controversy erupted, which of course consumed everybody's attention.
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Stranger still, was the fact that the first time I sat on a tube train, many of the passengers seemed to be totally oblivious to the startling contents at the front of these papers, and were reading them backwards - starting with the sport pages, not even reading the pages where an attempt at telling the news might be.
That marked the first time since 1981, when data were first available, that motor vehicle crashes were not among the nation's top 10 causes of death.
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